An experiment was conducted to evaluate the efficacy of epidural bacterial filters (pore size 22nm) in the filtration of pathogenic bacteria from clear intravenous (IV) fluids. Fifty mL of sterile dextrose was mixed with a known quantity of bacteria and infused through an epidural bacterial filter by a syringe pump at a rate of 2 ml per hour for 24 hours. Cultures were done from the remaining f...

Neutrinos, being the only fermions in Standard Model of Particle Physics that do not possess electromagnetic or color charges, have unique opportunity to communicate with outside through mass mixing. Such Model-singlet are generally referred as “sterile neutrinos”. In this review article, we discuss theoretical and experimental motivation for sterile neutrinos, well their phenomenological conse...

The aim of this study was to evaluate the impact of different inactivation and splitting procedures on influenza vaccine product composition, stability and recovery to support transfer of process technology. Four split and two whole inactivated virus (WIV) influenza vaccine bulks were produced and compared with respect to release criteria, stability of the bulk and haemagglutinin recovery. One ...

Helix-hairpin-helix (HhH) is a widespread motif involved in non-sequence-specific DNA binding. The majority of HhH motifs function as DNA-binding modules, however, some of them are used to mediate protein-protein interactions or have acquired enzymatic activity by incorporating catalytic residues (DNA glycosylases). From sequence and structural analysis of HhH-containing proteins we conclude th...

Streptococcus pyogenes type 12, isolated from the pharynx of a patient with acute poststreptococcal glomerulonephritis, was subcultured in Todd-Hewitt broth and incubated at 37°C for 24 hr. The organisms were removed by centrifugation and washed with Dulbecco’s solution, and serial dilutions were plated on blood-agar plates; 1 ml of suspension containing 3 x 104 organisms was used for treatment...

BACKGROUND Aedes aegypti Linnaeus is a peridomestic mosquito that lays desiccation-resistant eggs in water-filled human-made containers. Previous investigations connected egg hatching with declining dissolved oxygen (DO) that is associated with bacterial growth. However, past studies failed to uncouple DO from other potential stimulatory factors and they contained little quantitative informatio...

INTRODUCTION Increased urine neutrophil gelatinase-associated lipocalin (uNGAL) concentrations are associated with the early phase of kidney damage. Urine NGAL may increase due to production by neutrophils present in urine, particularly in patients with urinary tract infections. The aim of the study was to assess the relationship between sterile leukocyturia and uNGAL concentrations in patients...

1. Acute tubular necrosis (ATN) with acute renal failure (ARF) was induced in rats with (a) a combination of subcutaneous (s.c.) cephaloridine 500 mg/kg, frusemide 50 mg/kg and 4 ml/kg of 50% (v/v) glycerol in sterile water, (b) S.C. cephaloridine 1500 mg/kg, (c) S.C. mercuric chloride 2.0 and 4.7 mg/kg and (d) both S.C. and intramuscular glycerol (10 ml/kg in sterile water). 2. Pretreatment of...