The emergence and spread of drug resistance is one of the most challenging public health issues in the treatment of some infectious diseases. The objective of this work is to investigate whether the effect of resistance can be contained through a time-dependent treatment strategy during the epidemic subject to an isoperimetric constraint. We apply control theory to a population dynamical model ...

Overview Diversion is the unauthorized transfer of arms and ammunition from the stocks of legal users to the illicit market. Throughout the world, it sustains the activities of non-state armed groups, terrorist organizations, and armed criminality. It is one of the principal sources of illicit weaponry and represents a grave threat to the safety of civilian populations, as well as to the securi...

Obsolete pesticides have accumulated in almost every developing country or economy in transition over the past several decades. Concerned about the risks these chemicals pose to nearby residents, public health and environmental authorities are eager to reduce health threats by removing and decontaminating stockpile sites. However, there are many sites, cleanup can be costly, and public resource...