Oxidative stress is a hallmark of retinal degenerations such as age-related macular degeneration and diabetic retinopathy. Enhancement of heme oxygenase-1 (HO-1) activity in the retina would exert beneficial effects by protecting cells from oxidative stress, therefore promoting cell survival. Because a crosstalk exists between nitric oxide (NO) and HO-1 in promotion of cell survival under oxida...

Santos, Javier, Paul R. Saunders, Nico P. M. Hanssen, Ping-Chang Yang, Derrick Yates, Jack A. Groot, and Mary H. Perdue. Corticotropin-releasing hormone mimics stress-induced colonic epithelial pathophysiology in the rat. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G391– G399, 1999.—We examined the effect of stress on colonic epithelial physiology, the role of corticotropin-releasing...

A new Room Temperature (RT) 0-level vacuum package is demonstrated in this work, using amorphous silicon (aSi) as sacrificial layer and SiO2 as structural layer. The process is compatible with most of MEMS resonators and Resonant Suspended-Gate MOSFET [1] fabrication processes. This paper presents a study on the influence of releasing hole dimensions on the releasing time and hole clogging. It ...

Control of the secretion of ACTH appears to involve several mechanisms. It is dependent upon the release, from neurones in the hypothalamus, of corticotrophin releasing factor, which is probably a complex including CRF-41 and vasopressin. The secretion of the complex is influenced by various central inhibitory and excitatory nervous pathways. The releasing factor is conveyed by the hypophyseal ...

We use ab initio density-functional calculations to study hydrogen-induced disintegration of single-wall and multiwall carbon fullerenes and nanotubes. Our results indicate that hydrogen atoms preferentially chemisorb along lines in sp2 bonded carbon nanostructures, locally weakening the carbon bonds and releasing stress. For particular structural arrangements, hydrogen helps to relieve the acc...

Postnatal maternal separation increases hypothalamic corticotropin-releasing factor (CRF) gene expression and hypothalamic-pituitary-adrenal (HPA) and behavioral responses to stress. We report here that environmental enrichment during the peripubertal period completely reverses the effects of maternal separation on both HPA and behavioral responses to stress, with no effect on CRF mRNA expressi...

The corticotropin-releasing factor (CRF) system, which is involved in stress, addiction, and anxiety disorders such as depression, acts through G-protein-coupled receptors (GPCRs) known as type-1 and type-2 CRF receptors. The purpose of this review is to highlight recent advances in the interactions of CRF receptors with other GPCRs and non-GPCR proteins and their associated functional conseque...

Potassium (K) is one of the essential macronutrients required for plants and its availability to hampered due fixation with other ions. The Releasing Micro-organisms (KRMs) present in soil are capable converting fixed form potassium into an available K uptake. Most commonly potash releasing bacteria rhizosphere belong phylum Firmicutes, Proteobacteria Actinobacteria. These microbes produce orga...

Chronic kidney disease (CKD) is a long-term where the kidneys have decreased function. In women who experience prolonged CKD, other problems will arise, namely Menstrual abnormalities. CKD patients just undergone hemodialysis therapy are prone to stress, if not treated immediately it disrupt menstrual cycle. This research design uses correlation analytic with cross sectional approach. The popul...

p0005 Corticotropin-releasing hormone [CRH; also referred to as corticotropin-releasing factor (CRF)] is a member of a family of related peptides in vertebrates that includes the fish urotensins-I, frog sauvagine, and the urocortin/stresscopin peptides. CRF was first named for its stimulatory effect on corticotropin [also known as adrenocorticotropic hormone (ACTH)] secretion from the anterior ...