introduction: the process of discriminating among benign and malignant hyperplasia begun with subjective methods using light microscopy and is now being continued with computerized morphometrical analysis requiring some features. one of the main features called volume percentage of stroma (vps) is obtained by calculating the percentage of stroma texture. currently, this feature is calculated by...

Crosslinking of ultrapure hemoglobin, crystalline catalase, and superoxide dismutase resulted in a soluble nanodimensional complex of polyhemoglobin-catalase-superoxide dismutase. A less expensive and more convenient way is to crosslink bovine stroma-free hemolysate (stroma-free hemolysate) that already contains hemoglobin, catalase, and superoxide dismutase into polyhemoglobin with catalase an...

In long-term bone marrow cultures, stroma-adherent progenitors proliferate significantly less than nonadherent progenitors. Thus, close progenitor-stroma interactions may serve to regulate or restrict rather than promote hematopoietic progenitor proliferation. We hypothesized that signaling through adhesion receptors on hematopoietic cells may contribute to the inhibition of proliferation obser...

It is the purpose of this paper to review recent investigations, including some unpublished studies on the metabolic and physiologic dependence of small areas of stroma on the overlying cells, with the object of assessing the extent to which they have contributed to a fuller understanding of the mechanism by which aerobic metabolism maintains the deturgescence of the corneal stroma. The recent ...

OBJECTIVE Tumor-stroma proportion of tumor has been presented as a prognostic factor in some types of adenocarcinomas, but there is no information about squamous cell carcinomas and laryngeal carcinomas. MATERIAL AND METHOD Five digital images of the tumor sections were obtained from 85 laryngeal carcinomas. Proportion of epithelial tumor component and stroma were measured by a software tool,...

Acellular corneal stroma matrix has been used for corneal stroma engineering. However, because of its compact tissue structure, regrowth of keratocytes into the scaffold is difficult. Previously, we developed a sandwich model for cartilage engineering using acellular cartilage sheets. In the present study, we tested this model for corneal stroma regeneration using acellular porcine corneal stro...