The objective of this work was to prepare hybrid nanoparticles of graphene sheets decorated with strontium metallic nanoparticles and demonstrate their advantages in bone tissue engineering. Strontium-decorated reduced graphene oxide (RGO_Sr) hybrid nanoparticles were synthesized by the facile reduction of graphene oxide and strontium nitrate. X-ray diffraction, transmission electron microscopy...

As an important step in the nuclear transfer (NT) procedure, we evaluated the effect of three different treatments for oocyte activation on the in vitro and in vivo developmental capacity of bovine reconstructed embryos: (1) strontium, which has been successfully used in mice but not yet tested in cattle; (2) ionomycin and 6-dimethylaminopurine (6-DMAP), a standard treatment used in cattle; (3)...

Osteoblastic differentiation from human mesenchymal stem cell (hMSCs) is an important step of bone formation. We studied the in vitro induction of hMSCs by using strontium ranelate, a natural trace amount in water, food and human skeleton. The mRNA synthesis of various osteoblast specific genes was assessed by means of reverse transcription polymerase chain reaction (RT-PCR). In the hMSCs cultu...

Dental enamel is currently of high informative value in studies concerning childhood origin and human mobility because the strontium isotope ratio in human dental enamel is indicative of geographical origin. However, many prehistoric burials involve cremation and although strontium retains its original biological isotopic composition, even when exposed to very high temperatures, intact dental e...

Osteoporosis is a progressive and debilitating disease characterized by a massive bone loss with a deterioration of bone tissues, and a propensity for a fragility fracture. Strontium ranelate is the first antiosteoporotic treatment that has dual mode of action and simultaneously increases bone formation, while decreasing bone resorption, thus rebalancing bone turnover formation. Strontium ranel...

Here, we introduce a highly porous functional mesoscopically silica-polymer composite based on silica monolith-conjugated thiourea/formaldehyde copolymer. The developed nanostructure enables selective and fast removal of the radioactive pollutants strontium (Sr[II]) cesium (Cs[I]) ions from contaminated seawater. silica/polymer was synthesized by introducing solution into tetramethoxy orthosili...

We report the observation of intense extreme ultraviolet (EUV) emission from incandescently heated atomic hydrogen and atomized strontium. Typically the emission of extreme ultraviolet light from hydrogen gas is achieved via a discharge at high voltage, a high power inductively coupled plasma, or a plasma created and heated to extreme temperatures by RF coupling (e.g. > 10 6 K) with confinement...

Osteoporosis was originally described in literature and art hundreds of years ago. Our ability to treat this disease lay dormant for centuries, but in the past 10 years, clinical trials have improved treatment options and efficacy. In this issue of the Journal , Meunier et al. 1 report on their study of the safety and effectiveness of strontium ranelate as a putative, novel therapy for osteopor...

Bioactive glasses (BG) which contain strontium have the potential to combine the known bone regenerative properties of BG with the anabolic and anti-catabolic effects of strontium cations. Here we created a BG series (SiO(2)-P(2)O(5)-Na(2)O-CaO) in which 0-100% of the calcium was substituted by strontium and tested their effects on osteoblasts and osteoclasts in vitro. We show that ions release...

Dissolution rates and apparent solubilities for synthetic hydroxyapatite in acetate buffers containing phosphate and strontium ions in the range of 10-3 to 10-2 M were determined under various pH and buffer conditions. Critical examination of the role of strontium with a physical model suggests that a calcium-strontium apatite surface complex may govern the driving force of the dissolution reac...