نتایج جستجو برای: sublingual administration

تعداد نتایج: 237714  

Journal: :Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology 2016

Journal: :International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2007
A Faúndes C Fiala O S Tang A Velasco

The aim was to review the current knowledge about the use of misoprostol alone for abortion induction during the first 12 weeks of pregnancy. Publications reporting experiences with misoprostol alone for pregnancy termination within the first 12 weeks of pregnancy were included in the analysis. Vaginal administration of 800 microg repeated up to three times at 6, 12 or 24 h intervals has an 85%...

Journal: :European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2015
Doaa Ahmed El-Setouhy Emad B Basalious Nevine Shawky Abdelmalak

Formulation of sublingual tablets of drugs with limited permeability poses a great challenge due to their poor absorption. In this study, bioenhanced sublingual tablets (BESTs) of zolmitriptan were prepared using novel surfactant binder (Pluronic® p123/Syloid® mixture) to enhance tablet disintegration and dissolution. Microencapsulated polysorbate 80 (Sepitrap™ 80) were included in the composit...

2015
Thiago Domingos Corrêa Stephan Matthias Jakob Jukka Takala

Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improv...

Journal: :Obstetrics and gynecology 2014
Jan E Dickinson Belinda G Jennings Dorota A Doherty

OBJECTIVE To compare the efficacy of the vaginal and sublingual administration of the synthetic prostaglandin misoprostol with the currently used oral administration route in second-trimester medical abortion. METHODS This was a prospective randomized trial of medical abortion with misoprostol after mifepristone priming at 14-24 weeks of gestation. From 2009 to 2013, recruited women received ...

Journal: :Respiratory medicine 2008
P Panzner M Petrás T Sýkora I Lesná

Forty-one patients suffering from grass pollen allergy underwent specific immunotherapy with standardized allergen extract consisting of six grass pollens (H-Al per os) administered either sublingually or supralingually for one year. In order to investigate clinical and immunological changes induced by the administration of allergens via the oral mucosa, the double-blind, placebo-controlled, ra...

Journal: :Japanese journal of pharmacology 1990
B Ceyhan Y Karaaslan O Caymaz A Oto E Oram A Oram S Ugurlu

Hypertensive crises require immediate therapy, usually by parenteral drug administration. Sublingual nifedipine has been shown to be highly effective. However, the blood pressure fall following nifedipine is frequently associated with side-effects. The use of sublingual captopril has recently been indicated in hypertensive crisis, assuming that by this route, there would be a faster absorption ...

2017
Tae-Hoon Kim Ho-Jun Jang Sihun Kim Sung Yun Cho Kyung Sun Song Christopher Pickett Heiko J Schmitt Juyong Lee

INTRODUCTION Increased adrenergic tone might be an additional trigger of orthostatic stress of vasovagal syncope (VVS). Exercise before standing might provide increased sensitivity compared to standing using a sublingual nitroglycerines protocol during tilt table testing. The aim of this study was to evaluate the diagnostic value of treadmill testing before standing with nitroglycerin administr...

2014
Vanina Siham Kanoore Edul Can Ince Noelia Navarro Luciana Previgliano Alejandro Risso-Vazquez Paolo Nahuel Rubatto Arnaldo Dubin

BACKGROUND This study was performed to compare intestinal and sublingual microcirculation and their response to a fluid challenge. METHODS Twenty-two septic patients in the first postoperative day of an intestinal surgery, in which an ostomy had been constructed, were evaluated both before and 20 min after a challenge of 10 mL/kg of 6% hydroxyethylstarch 130/0.4. We measured systemic hemodyna...

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