BACKGROUND In low-resource settings, where abortion is highly restricted and self-induced abortions are common, access to post-abortion care (PAC) services, especially treatment of incomplete terminations, is a priority. Standard post-abortion care has involved surgical intervention but can be hard to access in these areas. Misoprostol provides an alternative to surgical intervention that could...

Article type: Original article Background & aim: Recently, the use of mifepristone followed by misoprostol after 36-48 h has been demonstrated to be an effective and safe method for the second trimester medical abortion. However, this regimen entails long total abortion time, and consequently increases the financial burden and anxiety in the patients. We hypothesize that one day interval would ...

STUDY QUESTION Can sublingual administration of misoprostol 1 h prior to vacuum aspiration be more effective than vaginal administration and as effective as either route three 3 h prior to surgery? SUMMARY ANSWER Sublingually administered misoprostol is superior to vaginally administered misoprostol when given 1 h pre operatively, and it is as effective as after a three 3 h priming interval w...

Objective: In the poor underdeveloped countries, anaemia is very common in pregnant women. Maternal mortality is four times higher in severely anaemic women than non-anaemic ones and postpartum haemorrhage (PPH) is the most common cause of death Its main cause is uterine atony, which accounts for more than 70%. The objective of this study is to evaluate the use of sublingual misoprostol in diff...

The aim was to review the current knowledge about the use of misoprostol alone for abortion induction during the first 12 weeks of pregnancy. Publications reporting experiences with misoprostol alone for pregnancy termination within the first 12 weeks of pregnancy were included in the analysis. Vaginal administration of 800 microg repeated up to three times at 6, 12 or 24 h intervals has an 85%...

99% of all deaths in childbirth are in the least developed countries. Annually, 45 million women deliver without a skilled birth attendant, a situation in which the greatest number of maternal deaths occur. In many low-resource settings, having enough skilled birth attendants remains a distant goal. The commonest single cause of maternal death is from post-partum haemorrhage, from which one wom...

BACKGROUND Complications following spontaneous or induced abortion are a major cause of maternal morbidity. To manage these complications, post-abortion care (PAC) services should be readily available and easy to access. Standard PAC treatment includes surgical interventions that are highly effective but require surgical providers and medical centers that have the necessary space and equipment....

Background: This hospital-based, prospective, comparative interventional study aimed to compare the effectiveness of sublingual misoprostol and intracervical dinoprostone gel for induction labor in primigravida women. Methods: A total 100 patients were alternately assigned with either Misoprostol 25mcg 6 hourly or Gel 0.5mg hourly. Results: The delivery interval was significantly longer group c...

Background: The idea of this study was to evaluate the efficacy and safety different routes administration misoprostol - 50µg oral, 25µg vaginal sublingual for induction labour in women with premature rupture membranes after 34 weeks gestation.Design: Randomized controlled trial.Sample: A total 252 gestation indications labour.Methods: Study conducted from 01/02/2022 31/11/2022, Women admitted ...

OBJECTIVES To compare the clinical effectiveness and cost-effectiveness of labour induction methods. METHODS We conducted a systematic review of randomised trials comparing interventions for third-trimester labour induction (search date: March 2014). Network meta-analysis was possible for six of nine prespecified key outcomes: vaginal delivery within 24 hours (VD24), caesarean section, uterin...