Cyclization and chlorination of 2-amino-5-benzyl-4, 5, 6, 7-tetrahydro hydro thieno [3, 2c] pyridine-3carboxamide yielded (3 a-b). Reaction with different substituted pyridines of [3 a-b] yielded 4a (1-4) and 4b (1-2). However reaction of 3a with different substituted 2-amino phenols yielded 4a (5-6). Further 3a yields 4a (7) & 4a (8) from different substituents like o-phenylene diamine and 4-c...

Hydrothermal (HT) treatment of seeds from Chinese privet (Ligustrum sinense), a non-native and invasive species in the southeastern United States, was examined with respect to the generation of gas-phase and semi-volatile organic chemicals of industrial importance from a lipid-rich biomass resource. Aqueous seed slurries were transformed into biphasic liquid systems comprised of a milky aqueous...

Transition-metal-catalyzed [4+2] heteroannulation of α,β-unsaturated oximes and their derivatives with alkynes has been developed into a powerful strategy for the synthesis pyridines. It nevertheless lacks regioselectivity when unsymmetrically substituted are used. We report herein unprecedented polysubstituted pyridines by formal [5+1] two readily accessible building blocks. A copper-catalyzed...

effects of imidazoles and substituted pyridines and pure s-donors on the oxidation of cyclooctene with naio4 by 5,10,15,20-tetraphenylporphyrinato-manganese(iii) acetate, mn(tpp)oac, and 5,10,15,20-tetramesitylporphyrinato-manganese(iii) acetate, mn(tmp)oac, catalysts in ch2cl2-h2o solvent are studied. coordination of the nitrogen donors to the mn-catalysts generally caused a reduction in the e...

A practical approach to highly functionalized 4-hydroxypyridine derivatives with stereogenic side chains in the 2- and 6-positions is described. The presented two-step process utilizes a multicomponent reaction of alkoxyallenes, nitriles and carboxylic acids to provide β-methoxy-β-ketoenamides which are transformed into 4-hydroxypyridines in a subsequent cyclocondensation. The process shows bro...

Three symmetrical and unsymmetrical trans-dithienylethenes functionalized with pyridines and fluorenes have been synthesized by a facile one-pot procedure, and their characteristics and photochromism were investigated. Their fluorescent intensity was efficiently regulated by a photochromic switch using alternative irradiation with UV light and visible light. Moreover, by protonation and complex...