نتایج جستجو برای: sulfonamide
تعداد نتایج: 2548 فیلتر نتایج به سال:
1. Strains of staphylococci produce diazotizable materials which can be converted to a dye, and the intensity of the color reaction can be quantitated in the same manner as p-aminobenzoic acid. The sulfonamide-resistant strains which we have studied produce more diazotizable substance than non-resistant strains. 2. The development of a color by the diazotizable substance can be inhibited by exp...
Thirteen novel 1, 2, 4-triazoles incorporating a biologically active sulfonamide moieties 1-13 were designed and synthesized. The structures of the prepared compounds were elucidated on the basis of elemental analyses, IR, H-NMR, C-NMR and mass spectral data. All the newly synthesized compounds were evaluated for their in vitro anticancer activity against various cancer cell lines. The correspo...
SUMMARY The effect of a single oral dose of 4-ethylsulfonylnaphtha lene-l-sulfonamide , 2-acetylaminofluorene , and 3-aminodi benzofuran on DNA, RNA, and protein synthesis in the urinary bladder and liver of the mouse has been investigated. Each chemical stimulated RNA and DNA synthesis in the bladder, but the magnitude and timing of the response was different in each case. Administration of 4-...
The title compound, C(9)H(12)N(2)O(2)S, is a useful precursor of a variety of modified sulfonamide mol-ecules. Due to the importance of these mol-ecules in biological systems (antibacterials, antidepressants and many other applications), there is a growing inter-est in the discovery of new biologically active compounds. In the title compound, the mol-ecules are linked by N-H⋯O inter-molecular h...
overcome. Sulfanilamide, sulfathiazole, sulfadiazene, and sulfapyridine were measured by the method of Bratton and Marshall (2), using a photoelectric colorimeter.2 Substrates and ultrafiltrates of serum were obtained according to Lavietes' method (3). It had been established previously that contact with mercury did not affect the determination of sulfonamide compounds in serum. The effects of ...
Cu-catalyzed aerobic oxidative three-component coupling of a terminal alkyne, secondary amine, and sulfonamide enables efficient synthesis of amidines. The use of Cu(OTf)2 (5 mol %) produces amidines selectively without Glaser-Hay alkyne homocoupling products. Preliminary studies suggest that the reaction pathway involves initial oxidative coupling of the terminal alkyne with the secondary amin...
The title compound, C12H18N4O6S (systematic name: 4-di-propyl-amino-3,5-di-nitro-benzene-sulfonamide), is a sulfonamide with herbicidal properties marketed as oryzalin. The dihedral angles between the benzene ring and the mean planes of the nitro groups are 26.15 (11) and 54.80 (9)°. The propyl arms of the di-propyl-amino substituent lie on opposite sides of this ring plane. In the crystal, N-H...
There are two mol-ecules in the asymmetric unit of the title compound, C(11)H(10)N(3)O(4)S(+)·NO(3) (-). All bond distances have normal values. The C-N bond distances in the sulfonamide group [1.389 (3) and 1.382 (3) Å] may indicate slight conjugation of the sulfonamide N-atom π-electrons with those of the pyridinium ring. The crystal structure is stabilized by N-H⋯O hydrogen bonds.
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