Highly toxic sulfur-containing gases have been pathogenetically implicated in ulcerative colitis. Utilizing a rat model, we studied the production and elimination of sulfur-containing gases within the unperturbed colon. The major sulfur-containing gases were hydrogen sulfide (H2S), methanethiol, and dimethyl sulfide with cecal accumulation rates of 2.6, 0.096, and 0.046 μl/min, respectively. Th...

Sulfur is an essential macro-element in plant and animal nutrition. Plants assimilate inorganic sulfate into two sulfur-containing amino acids, cysteine and methionine. Low supply of sulfate leads to decreased sulfur pools within plant tissues. As sulfur-related metabolites represent an integral part of plant metabolism with multiple interactions, sulfur deficiency stress induces a number of ad...

Leaves of woad (Isatis tinctoria L.) were found to incorporate efficiently tritiated indoleacetaldoxime and (35)S from (35)S-l-cystine into glucobrassicin and sulfoglucobrassicin. Time course of incorporation of (35)S from (35)S-cystine into the glucosinolates indicated that glucobrassicin was formed first and then sulfoglucobrassicin. Simultaneous administration of tritiated indoleacetaldoxime...

Sulfur mustard is a synthetic organic compound. It was first manufactured in 1822 by the action of ethene on sulfur monochloride or dichloride. Since then, the methods of manufacture have been refined, although they have not been changed substantially. Three main processes have been used. The Germans produced sulfur mustard using the Meyer process, which involved treating ethylene with hypochlo...

Observations in enrichment cultures of ferric iron-reducing bacteria indicated that ferrihydrite was reduced to ferrous iron minerals via sulfur cycling with sulfide as the reductant. Ferric iron reduction via sulfur cycling was investigated in more detail with Sulfurospirillum deleyianum, which can utilize sulfur or thiosulfate as an electron acceptor. In the presence of cysteine (0.5 or 2 mM)...

p-tert-Butyltetrathiatetramercaptocalix[4]arene, [S(4)Calix(Bu(t))(SH)(4)], reacts with Mo(PMe(3))(6), W(PMe(3))(4)(eta(2)-CH(2)PMe(2))H and Ni(PMe(3))(4) to yield molybdenum, tungsten and nickel compounds in a sulfur-rich coordination environment.

Allyl sulfur compounds are the major active constituents found in crushed garlic. Research has revealed that garlic and its lipid- or water-soluble components have many pharmacologic properties; however, studies also demonstrate that heating has a negative influence on these beneficial effects. We recently conducted several studies to investigate the influence of microwave or oven heating on th...

1,2,4-Benzotriazine 1,4-di-N-oxides are potent antitumor drug candidates that undergo in vivo bioreduction leading to selective DNA damage in the low oxygen (hypoxic) cells found in tumors. Tirapazamine (TPZ) is the lead compound in this family. Here we report on the synthesis, crystal structure, and conformational analysis of a new analog, 3-cyclopropyl-1,2,4-benzotriazine 1,4-di-N-oxide (3). ...

Sulfur is a low-toxicity element in its elemental form, but when combusts with air becomes sulfur dioxide, an irritating and toxic compound. This compound is released from many combustion processes because of the fact that different fuels such as coal, petroleum, diesel or natural gas contain certain amounts of sulfur. Therefore, nowadays there is a clear need to develop analytical methodologie...