THE use of the drugs known as "sulphonamides for the prevention and treatment of wound sepsis" is a subject of obvious importance at the present time, and much attention has recently been directed to the employment of sulphonamides by topical application for this purpose. This interest is reflected in the many enquiries received by the Medical Department of Messrs. May & Baker Ltd. of Dagenham,...

(Pp. 52. 9s.) Hong Kong UnivCrsity Press. London: Oxford University Press, 19%2. THIS book is an introduction to the use of statistical methods in the analysis of snmall samples of data. The author describes, with simple numerical examples, the arithmetic steps in computing averages, measures of dispersion, corielation coefficients, including partial coefficients vith one variable held constant...

THE use of the drugs known as "sulphonamides for the prevention and treatment of wound sepsis" is a subject of obvious importance at the present time, and much attention has recently been directed to the employment of sulphonamides by topical application for this purpose. This interest is reflected in the many enquiries received by the Medical Department of Messrs. May & Baker Ltd. of Dagenham,...

Selection by sulphonamides was investigated in Neisseria gonorrhoeae because a sulphonamide-resistant (Sulr), methionine-requiring (Met-) phenotype that was common in the era of sulphonamide therapy became rare in the penicillin era. Cultures of wild-type (SulsMet+) gonococci on a conventional medium containing sulphadiazine (2-10 micrograms ml-1) yielded numerous, nonidentical mutations of two...