3 Robert Meller, D.Phil., Roger P. Simon, MD 2 4 5 Translational Stroke Program, Neuroscience Institute, Morehouse School of Medicine, 6 Grady Memorial Hospital, Atlanta, GA USA 7 8 Running Title: Mechanisms of remote preconditioning 9 10 Correspondence: Robert Meller, Neuroscience Institute, Morehouse School of 11 Medicine, 720 Westview Dr SW, Atlanta, 30310. Tele 4047565789: Email 12 rmeller@...

OBJECTIVE It has been shown that oxidative stress plays an important role in development of noise induced hearing loss. Since static magnetic fields (SMF) exposure may alter dynamics of oxidative processes in the tissue, the aim of the study was to assess the influence of SMF on noise-induced alteration in the cochlear level of reactive oxygen species (ROS) and hearing thresholds. MATERIALS A...

The present study was carried out using mice model of chronic fatigue syndrome (CFS) in which mice were forced to swim everyday for 7 days for a 6 min session. There was a significant increase in despair behavior (immobility period) in saline treated mice on successive days. Treatment with potent antioxidants carvedilol (5 mg/kg, i.p.) and melatonin (10 mg/kg, i.p.) produced a significant reduc...

Hydroalcoholic extract of Andrographis paniculata prevented isoproterenol induced increase in lipid peroxidation and increased the activities of antioxidant enzymes viz. super oxide dismutase, catalase, glutathione peroxidase and the levels of reduced glutathione in hearts. In addition, the extract also prevented the leakage of lactate dehydrogenase from heart and salvages the heart from isopro...

Treatment with amiodarone, a commonly prescribed antidysrhythmic agent, is associated with pulmonary fibrosis (PF) which is a commonly progressive and untreatable disease. Caffeic acid phenethyl ester (CAPE) is a phenolic antioxidant and an active anti-inflammatory , anticancer, antimicrobial and antioxidant component of propolis (bee glue; a resinous hive product collected by honey bees). In t...

this study was conducted to investigate the effect of different levels of savory (satureja hortensis) powder and its essential oil on performance and antioxidant status of broiler chickens under heat stress (34±2 ˚c for 8 hours per day). a total of 336 one-day-old male broiler chicks (ross-308) were divided into 6 treatments and 4 replications (14 birds per replicate). experimental diets were a...

ischemia reperfusion injury (ir injury) is a common problem in clinical conditions. researches have frequently revealed that atp- sensitive potassium (katp) channels and nitric oxide plays a role in protection against ischemic injury in skeletal muscle. the present study aimed at evaluating the possible link between this two pathways. sixty-eight male wistar rats, were pretreated with saline, d...

Root growth and protective enzymes of Festuca arundinacea L. and Lolium perenne L. under Cu stress were investigated in a hydroponic experiment. Cu stress significantly inhibited root growth (root elongation and dry biomass) of both turfgrasses. Malondialdehyde (MDA) content in roots of both turfgrasses markedly increased under copper stress. In F. arundinacea root, superoxide dismutase (SOD) a...

The paperaim of the was to study the effect of low temperature stress on Avena nuda L. seedlings. Cold stress leads to many changes of physiological indices, such as membrane permeability, free proline content, malondialdehyde (MDA) content, and chlorophyll content. Cold stress also leads to changes of some protected enzymes such as peroxidase (POD), superoxide dismutase (SOD), and catalase (CA...

this study aimed to assess the response of chickpea genotypes to drought stress in terms of morphological traits and subsequent biochemical changes to further understanding of drought resistance mechanisms in plants and access to better genetic resources. the chickpea genotypes including mcc776, mcc877, mcc696 and mcc588 evaluated at four soil moisture regimes with field capacity (control), 75%...