While Korea does not have any legal statement on surrogacy, treatments are carried out in practice. As a result, every Institutional Review Board (IRB) of each fertility clinic faces an ethical predicament in reviewing each case. There is a need to arrange the institutions' own standards of surrogate pregnancy procedures before the establishment of national or professional regulation. This arti...

A two-stage model for evaluating both trial-level and patient-level surrogacy of correlated time-to-event endpoints has been introduced, using patient-level data when multiple clinical trials are available. However, the associated maximum likelihood approach often suffers from numerical problems when different baseline hazards among trials and imperfect estimation of treatment effects are assum...

There has been great recent interest in the medical and statistical literature in the assessment and validation of surrogate endpoints as proxies for clinical endpoints in medical studies. More recently, authors have focused on using metaanalytical methods for quantification of surrogacy. In this article, we extend existing procedures for analysis based on the accelerated failure time model to ...

Background: There has been little interest in the research literature on public opinions regarding assisted conception and surrogacy, particularly in Iran. Nevertheles, the growing evidence shows that problems in adaptation and coping may be related to perceived normative values. Materials and Methods: In this cross sectional study, questionnaires on attitudes to surrogacy were completed by 187...

Surrogacy is a family building option for people unable to conceive or carry pregnancy. In heterosexual couples seeking surrogacy, woman who not the intended father’s partner, facilitates this Whilst normative discourses reinforced by contemporary healthcare policies highlight importance of involving fathers throughout pregnancy, little known about heterosexually partnered men’s experiences sur...

Providing health care for a woman with a surrogate pregnancy involves unique challenges. Although the ethical debate surrounding surrogacy continues, Canada has banned commercial, but not altruistic, surrogacy. In the event of a custody dispute between a surrogate mother and the individual(s) intending to parent the child, it is unclear how Canadian courts would rule. The prenatal health care p...

Background One of the most controversial issues related to the human embryo is the determination of the moment when an embryo is considered a human being and acquires a moral status. Although personhood and moral status are frequently mentioned in medical ethics, they are considered interdisciplinary as concepts that shape the debate in medical law (fiqh) since their consequences are influentia...

This paper provides an overview of surrogacy and the potential complexities involved in commissioning a surrogate baby. It reflects on the lead author’s previous surveys on this difficult topic that were conducted in 1997 and 2003. It offers an insight into the legal and ethical viewpoints on the matter that are held by various countries. Introduction: What is a Surrogate? Van Den Akker (2010) ...

Background: During recent years, scientists have presented several methods for treating infertility; these methods occasionally are highly efficient for infertile couples but can be concerning because of legal and ethical issues. One of these methods is surrogacy. Surrogacy is used when the main etiology of infertility is in the uterus caused by these three reasons: lack of uterine‚ congenital ...