SWI/SNF is an ATP-dependent remodeler that mobilizes nucleosomes and has important roles in gene regulation. The catalytic subunit of SWI/SNF has an ATP-dependent DNA translocase domain that is essential for remodeling. Besides the DNA translocase domain there are other domains in the catalytic subunit of SWI/SNF that have important roles in mobilizing nucleosomes. One of these domains, termed ...

Saltwater intrusion (SWI) is a type of pollution that adversely affects the quality groundwater in coastal aquifers. The Nile Delta aquifer (NDA) Egypt contains large amount freshwater. Increasing abstraction from and sea level rise have led to an increase SWI, which has reached up 100 km inland. Therefore, practical measures are required prevent further SWI. This study aims identify optimal we...

To evaluate malignant middle cerebral artery (MCA) infarction (defined as space-occupying edema in more than 50% to 75% of the MCA territory) on magnetic resonance imaging (MRI) with susceptibility-weighted imaging (SWI) sequence and assess the usefulness of SWI findings, diffusion-weighted imaging (DWI) findings, and apparent diffusion coefficient (ADC) as predictors of clinical outcome.Data f...

BACKGROUND AND PURPOSE Cerebral microbleeds are thought to have potentially important clinical implications in dementia and stroke. However, the use of both T2* and SWI MR imaging sequences for microbleed detection has complicated the cross-comparison of study results. We aimed to determine the impact of microbleed sequences on microbleed detection and associated clinical parameters. MATERIAL...

A systems understanding of nuclear organization and events is critical for determining how cells divide, differentiate, and respond to stimuli and for identifying the causes of diseases. Chromatin remodeling complexes such as SWI/SNF have been implicated in a wide variety of cellular processes including gene expression, nuclear organization, centromere function, and chromosomal stability, and m...

SWI-Prolog is a Prolog implementation based on a subset of the WAM (Warren Abstract Machine). SWI-Prolog was developed as an open Prolog environment, providing a powerful and bi-directional interface to C in an era this was unknown to other Prolog implementations. This environment is required to deal with XPCE, an object-oriented GUI system developed at SWI. XPCE is used at SWI for the developm...

1. Abstract 2. Introduction 2.1. Histone acetyltransferase and deacetylase complexes 2.2. SWI/SNF family of chromatin remodeling complexes 3. Activator targeting of histone acetyltransferase complexes 4. Activator targeting of SWI/SNF complexes 5. Communication between HATs and SWI/SNF at promoter nucleosomes 6. Repressor targeting of histone deacetylase complexes 7. Perspectives 8. Acknowledge...

Findings on Susceptibility-Weighted Imaging Developmental venous anomaly (DVA) is the most common type of vascular malformation found at autopsy, with a prevalence of 2%. DVA is composed of radially arranged venous complexes converging to a centrally located venous trunk, which drains the normal brain parenchyma. Susceptibility-weighted imaging (SWI) shows low signal intensity for DVA due to th...

BACKGROUND AND PURPOSE Asymmetric hypointensity of cerebral veins on susceptibility-weighted imaging has been shown to indirectly reflect tissue hypoxia after cerebral ischemia. We therefore investigated whether patients with prominent asymmetry of the cerebral veins on SWI and a relatively small diffusion-weighted imaging lesion (SWI-DWI mismatch), representing the presence of salvageable tiss...