نتایج جستجو برای: synaptic terminal
تعداد نتایج: 207353 فیلتر نتایج به سال:
BACKGROUND Previous work by our lab and others has implicated glutamate as a major excitatory signal to gonadotropin hormone releasing hormone (GnRH) neurons, with gamma amino butyric acid (GABA) serving as a potential major inhibitory signal. However, it is unknown whether GABAergic and/or glutamatergic synaptic appositions to GnRH neurons changes on the day of the proestrous LH surge or is af...
Abstract This paper reports on the demonstration of gate-tunable plasticity in artificial synaptic devices based four-terminal planar memristors with amorphous gallium oxide as a memristive material. Reproducible resistance switching properties were obtained by applying voltages to four terminals, indicating two-dimensional modulation oxygen vacancy distribution. Based resistive properties, was...
Electrospun nanofibers have become the most promising building blocks for future high-performance electronic devices because of advantages larger specific surface area, higher porosity, more flexibility, and stronger mechanical strength over conventional film-based materials. Moreover, along with properties ease fabrication cost-effectiveness, a broad range applications based on nanomaterials b...
Mutations in the leucine-rich repeat kinase 2 gene (LRRK2) are associated with familial and sporadic Parkinson's disease (PD). LRRK2 is a complex protein that consists of multiple domains, including predicted C-terminal WD40 repeats. In this study, we analyzed functional and molecular features conferred by the WD40 domain. Electron microscopic analysis of the purified LRRK2 C-terminal domain re...
Axoaxonal synapses impinge on the terminals of neurons and are thought to play a crucial role in the regulation of synaptic transmission. In the crayfish brain, the terminals of several identified interneurons exhibit both EPSPs and IPSPs in response to cephalic sensory stimulation. The terminal arbors extend into primary sensory neuropils near the terminals of primary afferent axons of the ant...
Mechanisms of local protein quality control in the presynaptic nerve terminal remain largely unknown. In this issue of Neuron, Uytterhoeven et al. (2015) describe a form of synaptic endosomal microautophagy controlling protein rejuvenation, critical for optimal synaptic activity.
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