Therapeutic use of biological response modulators in combination with chemotherapeutic drugs may propose a more efficient way for cancer therapy with fewer side effects. However, the related mechanism has not been well understood. Γ-interferon is a modulator of biological responses that inhibits the growth of malignant cells and mediates their differentiation. In this investigation, T cell lymp...

OBJECTIVES In this study we examined the in vitro synergistic effect of baicalin, the flavone constituent of Scutellaria spp., in combinations with oxytetracycline and tetracycline on the growth of Staphylococcus aureus. METHODS The MICs were determined by the broth microdilution method and the effect of combinations was evaluated according to the sum of fractional inhibitory concentration in...

The sequential application of ozone, chlorine dioxide, or UV followed by free chlorine was performed to investigate the synergistic inactivation of Bacillus subtilis spores. The greatest synergism was observed when chlorine dioxide was used as a primary disinfectant followed by secondary disinfection with free chlorine. A lesser synergistic effect was observed when ozone was used as the primary...

purpose: to report and review a rare variant of duane's syndrome named synergistic divergence and its surgical results. patient and findings: a 16-year-old girl presented with left face turn and reduced vision in both eyes. best corrected vision was od: 3/10 and os: 10/10. there was severe adduction deficiency of the re with simultaneous abduction of the re in left gaze. she had xt= 35 in ...

Valproic acid (VPA), a well-known histone deacetylase (HDAC) inhibitor, is used as an anti-cancer drug for various cancers, but the synergistic anti-cancer effect of VPA and doxorubicin (DOX) combination treatment and its potential underlying mechanism in hepatocellular carcinoma (HCC) remain to be elucidated. Here, we evaluate the mono- and combination-therapy effects of VPA and DOX in HCC and...

amitraz is one of the pesticides which is used in a vast area for controlling of the common pistachio psyllid, agonoscena pistaciae (hem.: aphalaridae). in this study the synergistic effect of piperonyl butoxide (pbo) on the toxicity of amitraz on adults of rafsanjan population of common pistachio psyllid was evaluated by residual contact vial (rcv) in laboratory conditions. the results showed ...

The incidence of invasive fungal infections is increasing in recent years. The present study mainly investigated glabridin (Gla) alone and especially in combination with fluconazole (FLC) against Cryptococcus neoformans and Candida species (Candida albicans, Candida tropicalis, Candida krusei, Candida parapsilosis and Candida Glabratas) by different methods. The minimal inhibitory concentration...