Autophagy is involved in many human diseases, such as cancer, cardiovascular disease and virus infection, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), influenza A virus (IAV) and coxsackievirus B3/B4 (CVB3/B4), so a drug screening model targeting autophagy may be very useful for the therapy of these diseases. In our study, we established a drug screening model based on...

Chemical investigation of the methanol crude extract dried flower buds Syzygium aromaticum (Myrtaceae) resulted in isolation seven known compounds; oleanolic acid (1), lignoceric (2), β-sitosterol (3), heneicosanoic (4), 5-hydroxy-7-methoxy-2-methylchromone (5), 5-hydroxy-7-methoxy-2,8-dimethylchromone (6) and vanillin (7). Their structures were elucidated using one-dimensional NMR spectroscopy...

Amaç: Bitkilerden elde edilen uçucu yağlar, geleneksel sentetik böcek öldürücülere çevre dostu alternatifler sağlayabilir. Bu çalışmada beş farklı esansiyel yağın (Thymus vulgaris, Piper nigrum, Syzygium aromaticum, Hypericum perforatum, Papaver somniferum) Musca domestica larvalarına karşı etkisinin değerlendirilmesi amaçlanmıştır. Yöntem: Her yağ çeşidinin üç dozu (% 1, % 3 ve 6) tekerrürlü o...

Antimicrobial activities of the crude ethanolic extracts of five plants were screened against multidrug resistant (MDR) strains of Escherichia coli, Klebsiella pneumoniae and Candida albicans. ATCC strains of Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus bovis, Pseudimonas aeruginosa, Salmonella typhimurium, Escherichia coli, Klebsiella pneumoniae and Candida...

OBJECTIVE To explore the in vitro antibacterial activity of ethanolic extracts of cinnamon (Cinnamomum zeylanicum; CIN), clove (Syzygium aromaticum, CLV) and cumin (Cuminum cyminum, CMN) against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA), from Kolkata, India. METHODS The CIN, CLV and CMN were tested for their antibacterial activity against MRSA by in vitro methods...

Anxiety is a physiological state characterized by somatic, emotional, cognitive and behavioral components. It is the displeasing feeling of fear and concern[1]. Anxiety affects most of the population, nearly one-eighth of the total population world-wide. Benzodiazepines, being major class of compounds used for treatment of anxiety, present a narrow margin of safety between the anxiolytic effect...

OBJECTIVE The beneficial effects of clove on toothache have been well documented. We have also previously shown the analgesic effects of clove essential oil. The present work was done to investigate the analgesic effects of the aqueous extract of clove using hot plate test. The possible role of opioid receptors in the analgesic effects of clove was also investigated using naloxone. MATERIALS ...

The essential oils of Cananga odorata (ylang ylang), Citrus sinensis (orange), Cymbopogon citratus (lemongrass), Cymbopogon nardus (citronella grass), Eucalyptus citriodora (eucalyptus), Ocimum basilicum (sweet basil) and Syzygium aromaticum (clove), were tested for their insecticide activity against Aedes aegypti, Culex quinquefasciatus and Anopheles dirus using the WHO standard susceptibility...