AIMS To analyse time trends of antihyperglycaemic therapy and glycaemic control in adult subjects with type 1, or type 2 diabetes between 2002 and 2014 in Germany/Austria. METHODS 184,864 adults with diabetes (35,144 type 1 diabetes (T1D), 149,720 type 2 diabetes (T2D)) from the DPV-database documented between 2002 and 2014 were included. Regression models were applied for antihyperglycaemic ...

Objective People with food insecurity experience type 2 diabetes (T2D) at higher rates than others while lacking the resources to manage disease. In order improve health of food-insecure individuals T2D, interventions must address nutrition multiple levels. Use Theory or Research Delivering Health utilizes healthy eating and active living lifestyle programs management for people T2D. Target Aud...

BACKGROUND In adulthood, autoimmune diabetes can present as non-insulin-requiring diabetes, termed as 'latent autoimmune diabetes in adults' (LADA). In this study, we investigated established type 1 diabetes (T1D) and type 2 diabetes (T2D) genetic loci in a large cohort of LADA cases to assess where LADA is situated relative to these two well-characterized, classic forms of diabetes. METHODS ...

The SLC2A10 gene encodes a glucose transporter and is located on chromosome 20q13, where evidence has been found for linkage to type 2 diabetes (T2D) in multiple studies. We investigated SLC2A10 as a T2D candidate gene in Finns. We did not confirm the previously reported association between Ala206Thr and fasting insulin and we observed no statistically significant evidence for T2D association w...

Gestational diabetes mellitus (GDM) affects 3-14% of pregnancies, with 20-50% of these women progressing to type 2 diabetes (T2D) within 5 years. This study sought to develop a metabolomics signature to predict the transition from GDM to T2D. A prospective cohort of 1,035 women with GDM pregnancy were enrolled at 6-9 weeks postpartum (baseline) and were screened for T2D annually for 2 years. Of...

Diabetes mellitus is one of the most prevalent chronic diseases in children. Diabetes mellitus is classified into four major types. Type 1, type 2, gestational, and other specific types. Type 1 diabetes (T1D) is caused by autoimmune destruction of the insulin-producing beta cells of the pancreas. Type 2 diabetes (T2D) results from a combination of insulin resistance and be‐ ta cell insulin secr...

Background Beta cell dysfunction and death are critical steps in the development of both type 1 2 diabetes (T1D T2D), but underlying mechanisms incompletely understood. Activation essential tumor suppressor transcription factor P53 was linked to beta vitro has been reported several mouse models cells humans with T2D. Therefore, we investigated specific role dysfunction, vivo.

Background and Objective. Continuous glucose monitoring (CGM) is shown to improve quality of life (QoL) in youth with type 1 diabetes (T1D), yet there limited data on CGM 2 (T2D). The objective was compare perceptions QoL between patients T1D T2D. Methods. Youth T2D (currently insulin therapy) without current participated a prospective study were given series questionnaires when starting interv...

background : this study aimed to investigate the association of seven common inflammatory diseases with type 2 diabetes (t2d) in the chinese mainland population. methods : participants were recruited from a great swathe of mainland from 2009 to 2013 for the cohort study. the demographic characteristics between patients with t2d or with inflammatory diseases, including age, sex, smoking status, ...

BACKGROUND The increasing number of people with chronic diseases challenges workforce capacity. Type 2 diabetes (T2D) can have work-related consequences, such as early retirement. Laws of most high-income countries require workplaces to provide accommodations to enable people with chronic disabilities to manage their condition at work. A barrier to successful implementation of such accommodatio...