One of the major steps toward the industrialization of the microbial product(s) is to optimize the cultivation conditions at the large-scale bioreactor and successfully control the microbial behavior within a large scale production environment. Statistical Design of Experiment was proven to optimize a vast number of microbial processes to achieve robustness and explore possible interactions...

The operating control parameters of injection flushing type of electrical discharge machining process on stainless steel 304 workpiece with copper tools are being optimized according to its individual machining characteristic i.e. material removal rate (MRR). Lower MRR during EDM machining process may decrease its’ machining productivity. Hence, the quality characteristic for MRR is set to high...

1. In poultry investigations, the main interest is often to study the effects of many factors simultaneously. Two or three level factorial designs are the most commonly used for this type of investigation. However, it is often too costly to perform when number of factors increase. So a fractional factorial design, which is a subset or a fraction of a full factorial design, is an alternative. Th...

To solve the problem of great number of test cases, and to force the configuration testing to be effective, combinatorial testing is proposed, using an Orthogonal Array Testing Strategy (OATS) as a systematic, statistical way of testing pair-wise interactions. This combinatorial approach to software testing uses models to generate a minimal number of test inputs so that selected combinations of...

This research article presents the Quality by Design (QbD)-finalised conditions for a method that uses liquid chromatography-tandem mass spectrometry for the determination of concentration of enzalutamide (ENZ), an atypical anticancer drug, in a drug formulation and in spiked plasma samples. Critical process attributes (CPA) considered to be the influential parameters in separation, identificat...

A multi-response optimization problem was developed in search of an optimal parametric combination to yield favorable bead geometry of bead-on-plate weldments produced by submerged arc welding. Taguchi’s L25 orthogonal array design was employed to optimize the results within experimental limits. The objective functions were selected in terms of responses of bead geometry, viz. height of reinfor...

To satisfy the volatile nature of today s markets, businesses require a significant reduction in product development lead times. Consequently, the ability to develop precise product sales forecasts is of fundamental importance to decision-makers. Over the years, many forecasting techniques of varying capabilities have been introduced. The precise extent of their influences, and the interactions...

The utilization of TiB2 particles reinforced aluminum (Al6063) metal matrix composite materials in many different engineering fields has undergone a tremendous increase. Accordingly, the need of accurate machining of composites has increased enormously; an attempt has been made to assess the factors influencing surface roughness and material removal rate on machining the composite. The orthogon...

With modernization and increase in the number of automobiles worldwide, the consumption of diesel and gasoline has enormously increased. In this experiment tri fuel concept was used according to that diesel and turpentine different proportion bled introduced in diesel engine and acetylene entre in the diesel engine through intake manifold in the diesel engine. Among the many process parameters,...

the taguchi method was applied as an experimental design to determine optimum conditions for colour removal from azo dyes solutions containing remazol yellow g by electrocoagulation (ec) using iron and steel electrodes as anode and cathode, respectively. an orthogonal array (oa9) experimental design that allows to investigation the simultaneous variations of four parameters (initial remazol ye...