Microdeletion of 22q11 is responsible for DiGeorge syndrome, velocardiofacial syndrome, congenital conotruncal heart defects, and related disorders. We report our experiences on prenatal diagnosis by fluorescence in situ hybridization (FISH) for 22q11 deletion in two fetuses with tetralogy of Fallot. Karyotyping and FISH of the parents revealed that one fetus inherited the disease from maternal...

The optimal management of patients with tetralogy of Fallot has to consider the individual intra-cardiac anatomy as the most important variable, together with the age and the body weight of the patient. In any case the potential advantages of a primary early repair should be weighted against the experience and expertise of the individual centre and/or surgical team in dealing with tetralogy of ...

A patient with tetralogy of Fallot who developed cyanosis and tachypnea during spontaneous attacks of paroxysmal atrial tachycardia had an increase in right-to-left shunting with a fall in arterial oxygen saturation from 96 to 43%. Duplication of the fast heart rate by atropine and atrial pacing reproduced these hemodynamic changes, while slowing the rate with propranolol reversed this effect. ...

A hemodynamic model has been developed for the patient with tetralogy of Fallot based on electrical circuit analog and oxygen balance equations. A computer program has been written for the model in the Fortran IV computer language. With the computer model it has been possible to simulate the physiologic conditions during exercise, squatting and hypoxic episodes in tetralogy of Fallot. In additi...

PATIENT Male, 0 FINAL DIAGNOSIS: Tetralogy of Fallot Symptoms: - MEDICATION - Clinical Procedure: - Specialty: Cardiology. OBJECTIVE Unusual or unexpected effect of treatment. BACKGROUND Tetralogy of Fallot (ToF) is the most common form of cyanotic congenital defect. Adult subjects with results of repair of tetralogy of Fallot may present post-surgical consequences that limit their physic...

A patient with tetralogy of Fallot who developed cyanosis and tachypnea during spontaneous attacks of paroxysmal atrial tachycardia had an increase in right-to-left shunting with a fall in arterial oxygen saturation from 96 to 43%. Duplication of the fast heart rate by atropine and atrial pacing reproduced these hemodynamic changes, while slowing the rate with propranolol reversed this effect. ...

BACKGROUND AND AIMS Patients with repaired tetralogy of Fallot may develop chronic right ventricular dysfunction and hepatic congestion over time. We hypothesized that bile acid metabolism is altered in repaired tetralogy of Fallot patients and therefore sought to correlate right ventricular indices with serum bile acid levels. METHODS Indexed right ventricular end diastolic volume, as assess...

DURING the past two decades great strides have been made in the surgical treatment of tetralogy of Fallot. Prior to 1944, only conservative medical treatment could be offered to these patients. Since the development of the systemic-pulmonary artery shunt operation that year,1 this procedure has been extensively employed all over the world. The symptomatic relief offered by this operation is wel...

conclusions using a single postsurgical dose of methylprednisolone does not significantly alter the clinical outcome after repairing tetralogy of fallot. results the only significant differences were lower incidence of bacteremia and higher incidence of hyperglycemia in the group who were used methylprednisolone. patients and methods one hundred children who underwent total repair of tetralogy ...