Transient global amnesia (TGA) is a dramatic event. Without warning, the patient suddenly experiences antegrade memory loss.1,2 As quickly as the amnesic syndrome appears, it resolves, usually within 24 hours. There are no apparent long-term sequelae, and recurrence is uncommon. What causes TGA? For years this question has been debated. Various proponents have advocated ischemic, migrainous, an...

The Mustard Operation is a surgical technique to correct a heart condition called the transposition of the great arteries (TGA). TGA is a birth defect in which the placement of the two arteries, the pulmonary artery, which supplies deoxygenated blood to the lungs, and the aorta, which takes oxygenated blood to the body are switched. William Thornton Mustard developed the operation later named f...

Transient global amnesia (TGA) is a well known clinical entity characterized by anterograde memory disturbance of sudden onset that lasts 1 to 24 hours. Orientation in space and time is impaired while consciousness remains undisturbed . TGA may refer to a single expression of several physiopathological phenomena. Conceptually, cerebral ischemia, epileptic discharge, and migraine constitute the ...

Transient global amnesia (TGA) is a neurological syndrome characterised by a self-limiting episode of isolated memory impairment. The aetiology of TGA is unknown but it is widely thought not to be an epileptic phenomenon. Nevertheless, epileptic seizures can cause a very similar clinical picture – the syndrome of transient epileptic amnesia (TEA). It is important to distinguish between these tw...

Objective This study evaluated alterations in cortical morphology in patients with transient global amnesia (TGA). Materials and Methods Diagnoses of TGA occurred at our hospital. Evaluation involved a structured interview to obtain clinical information and a brain magnetic resonance imaging scan. We analyzed whole-brain T1-weighted MRI data using FreeSurfer 5.1. Measures of cortical morpholo...

PURPOSE Transient global amnesia (TGA) is a syndrome of unknown etiology. Electroencephalographic (EEG) abnormalities in TGA have been reported previously. We analyzed the frequency and characteristics of EEG abnormalities in patients with TGA. METHODS We collected EEGs of patients with a clinical diagnosis of TGA who had visited the emergency room or the outpatient clinic over a period of 8 ...

Higher sensitive transglutaminase autoantibody (TGA) assay will detect the onset of celiac disease (CD) autoimmunity earlier. In developing a nonradioactive assay for TGA, we utilized electrochemiluminescence (ECL) technology and compared it to a high-performance radioimmunoassay (RIA) currently being used to screen patients with type 1 diabetes (T1D) and genetically at-risk individuals for CD....

An unexpectedly high proportion of TGA nonsense mutations was obtained in a collection of chemically induced mutations in the spoIIR locus of Bacillus subtilis. Of 11 different mutations obtained, TGA mutations were found in four codons, whereas only three codons yielded missense mutations. Six suppressors of the TGA mutations were isolated, and five of the suppressing mutations were mapped to ...