BACKGROUND Thalassemia syndromes are highly prevalent in Southeast Asia. In Thailand, high performance liquid chromatography (HPLC) is the most common technique routinely performed in diagnosis of thalassemia and hemoglobinopathies, while isoelectric focusing (IEF) is rarely employed. We compared the diagnostic utility of IEF and HPLC in neonatal screening for thalassemia and non-sickling hemog...

0

background: iron deficiency anemia (ida) is an important health problem all around the world especially in developing countries. in the mediterranean countries another prevelant reason of anemia is thalassemia. certain strategies had been established as a government policy to reduce prevalence in north cyprus, such as pre-marital screening of thalassemia. the prevalence of thalassemia trait has...

The study aimed to determine the effect of an educational program on parents' knowledge about chelation therapy, and nutrition their children with beta thalassemia major. A quasi experimental was carried out at Thalassemia Center in Al-Najaf City during periods 25 ͭ ͪ February 2021 15 March 2022. Non-probability (purposive) sample (70) parents were selected from center (38 mothers 32 fathers).The...

Background Chronic nature of thalassemia causes changes in different aspects of life in patients, including their self-efficacy. The aim of this study was to determine the effect of family-centered empowerment program on the self-efficacy of adolescents with Thalassemia major. Methods A quasi-experimental study was performed on adolescents with thalassemia major in 2013 in Bandar Abbas, Iran....

α-Thalassemia commonly results from deletions or point mutations in one or both α-globin genes located on chromosome 16p13.3 giving rise to complex and variable genotypes and phenotypes. Rarely, unusual non-deletion defects or atypical deletions down-regulate the expression of the α-globin gene. In the last decade of the program for β-thalassemia carrier screening and genetic counseling in Sard...

BACKGROUND Interpreting the erythroid lineage in populations with high frequency of α+ thalassemia allele is challenging due to the high prevalence of α+ thalassemia homozygotes. For such populations, separate reference values for normal and α+ thalassemia homozygotes are needed. METHODS We studied the erythroid lineage in 1,079 citizens of United Arab Emirates (UAE). Subjects with abnormal h...

INTRODUCTION Our information about renal involvement in beta-thalassemia major is limited. Recently, few studies have reported proteinuria, hypercalcuria, phosphaturia, and oversecretion of tubular damage markers; however, hematuria has not yet been meticulously studied in these patients. We investigated hematuria in patients with beta-thalassemia major. MATERIALS AND METHODS Urinalysis was p...

Background: Thalassemia is the most common hereditary disease in Iran. Cardiac complications and cardiac symptom have been identified as the major problem, which has profound impact on the mental health of patients with thalassemia. One method of reducing this impact is an exercise plan. Aim: The purpose of this study was to examine the effect of a designed Walking plan on the mental health and...