نتایج جستجو برای: the epithelial thickness of hair root sheath
تعداد نتایج: 22823130 فیلتر نتایج به سال:
Trichohyalin is a structural protein that is produced and retained in the cells of the inner root sheath and medulla of the hair follicle. The gene for sheep trichohyalin has been purified and the complete amino acid sequence of trichohyalin determined in an attempt to increase the understanding of the structure and function of this protein in the filamentous network of the hardened inner root ...
Hair follicle morphogenesis requires coordination of multiple signals and communication between its epithelial and mesenchymal constituents. Cell adhesion protein platforms, which include integrins and integrin-linked kinase (ILK), are critical for hair follicle formation. However, their precise contribution to this process is poorly understood. We show that in the absence of ILK, the hair foll...
Abstract Background: Considering the ineffective conventional therapeutic methods for treating different types of wounds, and because of reports of successful use of skin substitutes prepared from co-cultured keratinocytes and fibroblasts on the scaffold of collagen, this study was performed to evaluate the skin substitute on experimentally induced wounds in rats. Materials and methods: Thi...
BACKGROUND Selective immunostaining for calretinin labels the innermost layer of the outer root sheath of normal hair follicles, which is difficult to distinguish with hematoxylin-eosin staining. OBJECTIVE The aim of this study was to determine whether immunohistochemistry for calretinin allows identification of cutaneous adnexal tumors with follicular differentiation towards cells of the out...
The search for more effective drugs for the management of common hair growth disorders remains a top priority, both for clinical dermatology and industry. In this pilot study, we report a pragmatic organotypic assay for basic and applied hair research. The patented technique produces microdroplets, which generate human folliculoid microspheres (HFMs), consisting of human dermal papilla fibrobla...
The combined effects of myosin II and actin enable muscle and nonmuscle cells to generate forces required for muscle contraction, cell division, cell migration, cellular morphological changes, the maintenance of cellular tension and polarity, and so on. However, except for the case of muscle contraction, the details are poorly understood. We focus on nonmuscle myosin and actin in the formation ...
Background & Aims: It is known that Hertwig's epithelial root sheath and stem cells of apical papilla (SCAP) can organize the odontoblast cells under favorable conditions resulting in continued formation of the root even after the pulp is necrotic. The aim of this case report was to demonstrate the continued development of the roots of an immature permanent tooth with necr...
Hair follicles harbor a heterogeneous regenerative cell pool and represent putative low-to-non-invasively available source of stem cells. We previously reported technology for culturing human melanocytes from the hair follicle outer root sheath (ORS) autologous pigmentation tissue engineered skin equivalents. This study translated ORS to horses. de-veloped culture equine (eMORS) forelock cultur...
Natural mutations in the LIPH gene were shown to be responsible for hair growth defects in humans and for the rex short hair phenotype in rabbits. In this species, we identified a single nucleotide deletion in LIPH (1362delA) introducing a stop codon in the C-terminal region of the protein. We investigated the expression of LIPH between normal coat and rex rabbits during critical fetal stages o...
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