glutamate-mediated excitotoxicity and neurodegeneration have been shown as pathophysiological hallmarks of multiple sclerosis (ms) and other autoimmune inflammatory cns disorders. n‑methyl‑d‑aspartate (nmda) receptors play a pivotal role in the mediation of neuronal glutamate excitotoxicity leading to cellular damage and apoptotic cell death. current treatment approaches targeting glutamate exc...

goldfish carassius auratus were subjected to either formalin (250 ppm) or nacl (10 ppt), over a 0.5-h period followed by 24-h freshwater exposure. serum biochemistry was monitored before exposure (0), immediately after (0.5) plus 3 and 24 h after exposure. results showed that both formalin and nacl treatments caused rapid increase in cortisol with a peak at 3 h, which did not recover until 24 h...

acceptance and commitment therapy (act) is a new development within behavioral therapy. its goal is to promote psychological flexibility. numerous studies show that suffering results when people attempt to avoid their inner experiences (experiential avoidance). this experiential avoidance often leads to rigid and inflexible behavior that also leads them to compromise their goals and what is imp...

ayurveda, the indian art of holistic medicine describes fasting in terms of upavasa and considers it as one among the depletion therapies.   besides the extensive explanations on the preventive purports of fasting, the classics have explicitly explained and exemplified the therapeutic importance of fasting while treating different diseases and dealing with different stages of the diseases. feve...