In previous part of this work factors influencing the thermal stability of polymer nanocomposite materials were indicated, such as chemical constitution of organic modifier, filler content, nanocomposites’ structure and the processing-dependent degree of homogenization of nanofiller, were presented. In this part the basic changes in thermal behaviour of different polymeric matrixes (e.g. polyol...

A selective, specific and stability-indicating gradient reverse phase high-performance liquid chromatographic (HPLC) method was developed for the determination of Ranitidine in presence of its impurities, forced degradation products and placebo substances such as saccharide and parabens. Ultraviolet detection was performed at 230 nm. Separate portions of the drug product and ingredients were ex...

this research is aimed to undertake a comparative study on stability and thermal degradation kinetics of un-irradiated and high energy protons irradiated polyvinyl butyral (pvb) based on weight loss analysis and non-isothermal approaches. the weight loss by the un-irradiated pvb upon heating was found to be in two stages but due to high energy protons accelerated exposure following by chemical ...

The thermal degradation of polyethylene (PE) was carried out in the absence and presence ofcatalystes X-Zeolite and Silica-Alumina at different temperatures. The optimum PE/Catalysisratio was 0.25:0.05 g/g, which produced highest degradation value. PE and PE/Catalysis werecharacterized by thermogravimetric analysis. The thermal degradation properties of polymerhave been studied by Infrared spec...

Nelfinavir mesylate is the first nonpeptidic protease inhibitor available in pediatric formulation. In the present paper the stability of nelfinavir mesylate under different stress conditions is evaluated using Fourier transform infrared spectroscopy. The drug is subjected to thermal degradation, photodegradation, acid hydrolysis, base hydrolysis and oxidation as per ICH guidelines. Differentia...

an hplc method for determination of mebeverine hydrochloride (mh) in the presence of its degradation products was developed. the degradation of mh was studied under hydrolysis, oxidative and photolysis stress conditions. under alkaline, acidic and oxidative conditions, degradation of mh was observed. the separation was performed using a symmetry c 18 column and a mixture of 50 mm kh 2 po 4 , ac...

the microstructure and thermal properties of the synthesized block copolymers and terpolymers via atom transfer radical polymerization (atrp) were studied. the mole fraction of the blocks and chain length of the pvac-b-pma block copolymers were estimated with 1h nmr spectroscopy.differential scanning calorimety measurement shows two different transitions at 36°c and 8°c assigned to pvac and pma...

In this investigation, sensitive and reproducible methods are described for quantitative determination of deflazacort in the presence of its degradation product. The method was based on high performance liquid chromatography of the drug from its degradation product on reverse phase using Acquity UPLC BEH C18 columns (1.7 µm, 2.1 mm × 150 mm) using acetonitrile and water (40:60 V/V) at a flow ra...

A gradient, reversed-phase liquid chromatographic (RP-LC) method was developed for the quantitative determination of Norethindrone in Norethindrone tablets, used to treat drug for contraception and hormone replacement therapy. The gradient LC method employs solutions A and B as mobile phase. The solution A contains a mixture Milli Q water, acetonitrile and tetrahydrofuran in the ratio of 40:30:...