Mechanistic studies of the enolization of 2-methylcyclohexanone mediated by lithium hexamethyldisilazide (LiHMDS; TMS2NLi) in toluene and toluene/amine mixtures are described. NMR spectroscopic studies of LiHMDS/ketone mixtures in toluene reveal the ketone-complexed cyclic dimer (TMS2NLi)2(ketone). Rate studies using in situ IR spectroscopy show the enolization proceeds via a dimer-based transi...

Elite athletes and coaches are in a constant search for training methods and nutritional strategies to support training and recovery efforts that may ultimately maximize athletes' performance. Recently, there has been a re-emerging interest in the role of ketone bodies in exercise metabolism, with considerable media speculation about ketone body supplements being routinely used by professional ...

BACKGROUND Raspberry ketone is the primary aroma compound found in raspberries and naturally derived raspberry ketone is a valuable flavoring agent. The economic incentives for the production of raspberry ketone, combined with the very poor yields from plant tissue, therefore make this compound an excellent target for heterologous production in synthetically engineered microbial strains. METH...

Banyak negara mengambil keputusan untuk melaksanakan pengajaran dan pembelajaran (PdP) atas talian dengan memanfaatkan Teknologi Maklumat Komunikasi (TMK). Walau bagaimanapun, didapati ramai guru matematik masih lemah dalam aspek penguasaan ilmu, pengkaedahan PdP, penggunaan kepercayaan serta sikap terhadap TMK pendidikan. Oleh yang demikian, perlaksanaan kajian ini adalah bertujuan mengenal pa...

OBJECTIVES Blood ketone (beta-hydroxybutyrate) measurements are suggested instead of urine ketone (acetoacetate) measurements in the diagnosis of diabetic ketoacidosis. Urine ketone examination is difficult and time consuming, and may result in an incorrect interpretation. Studies performed in emergency departments on blood ketones are limited. Our objective is to compare urine ketones and capi...

Monocarboxylates have been implicated in the control of energy homeostasis. Among them, the putative role of ketone bodies produced notably during high-fat diet (HFD) has not been thoroughly explored. In this study, we aimed to determine the impact of a specific rise in cerebral ketone bodies on food intake and energy homeostasis regulation. A carotid infusion of ketone bodies was performed on ...

How do we build computational models of computation itself? This paper analyzes two such modeling languages from the perspective of building a third language which integrates their advantages. The ZD language Liver & Allemang, 1985, Allemang, 1997] models software components and conngurations in support of veriication and reuse. models intelligent systems in support of failure-driven learning a...

It is now well established that ketone bodies (acetoacetate and D-3-hydroxybutyrate) are metabolized by many mammalian tissues and that the rate of utilization is mainly dependent on their availability in the circulation. The aim in this contribution is to summarize briefly the pathways of ketone-body metabolism and to discuss the role of ketone bodies m various tissues. For a detailed review o...