Respiratory syncytial virus is a leading cause of lower respiratory tract infection in infants. Disease severity has been linked to host immune responses and polymorphisms in genes associated with innate immunity. A large-scale genetics study of single nucleotide polymorphisms (SNPs) in children in the Netherlands identified SNPs in the vitamin D receptor (VDR) and JUN genes which have a strong...

s, Posters and Oral presentation on national and international conferences 1. Blazsek A., Farkas L., Nyitray L.: Miozin Rúd Fragmentumok Vizsgálata, Avagy Egy Molekuláris Cipzárban Rejlő Lehetőségek. Xxvi. Biológus Otdk 2. Blazsek A., Ifj. Gergely P. , Zs. Weiszhár, K. Beke, G. Poór: Tt Vírus Kimutatása Autoimmun Reumatológiai Megbetegedésekben. Mit Xxxiv. Vándorgyűlés 3. Zs. Weiszhár, Ifj. Ger...

Toll-like receptor 4 (TLR4)-mediated recognition of lipopolysaccharide (LPS) is required for efficient recognition of Gram-negative bacterial infections. Two commonly occurring mutations in the human TLR4 gene (Asp299Gly and Thr399Ile) have recently been shown to be associated with blunted physiological responses to inhaled LPS, and with increased risk of Gram-negative bacteraemia in sepsis pat...