BACKGROUND Blood-contacting devices have contributed to improving the treatment of patients. However, thrombus formation at the interface between a connector and tube is still a potential source of thrombus-related complications that induce stroke or myocardial infarction. We aimed to develop a non-blood-contacting real-time method for visualizing thrombus formation, and to experimentally inves...

We aimed at comparing the sensitivity of magnetic resonance (MR) susceptibility-weighted imaging (SWI) with computed tomography angiography (CTA) in the detection of middle cerebral artery (MCA) thrombus in acute stroke. Seventy-nine patients with acute MCA stroke was selected using our search engine software; only the ones showing restricted diffusion in the MCA territory on diffusion-weighted...

Portal vein tumor thrombus is a frequent, challenging complication in hepatocellular carcinoma. Hepatocellular carcinoma patients with portal vein tumor thrombus may show worse liver function, less treatment tolerance and worse prognosis than patients without portal vein tumor thrombus, and they may be at higher risk of comorbidity related to portal hypertension. Western and some Asian guidelin...

OBJECTIVE It has been suggested that the intraluminal thrombus of abdominal aortic aneurysms (AAAs) predisposes for AAA rupture. Here, we examined the possibility that the intraluminal thrombus influences expression and activity of matrix-degrading proteases in the AAA wall. METHODS AND RESULTS Twenty patients undergoing elective repair of AAAs were included. From each patient, specimens from...

One hundred five unselected and consecutive patients were prospectively studies after acute transmural myocardial infarction to assess the incidence of mural thrombus formation and to relate the presence of thrombus to patient outcome in terms of systemic embolic events, functional class and survival. In 87 patients, optimal quality two-dimensional echocardiographic studies were obtained and we...

Microbubbles In article 2202281 by Jiang Li, Haosheng Chen, and co-workers, nanodroplet-coated microbubbles (NCMBs) are designed to realize a two-step cavitation strategy accelerate thrombolysis. The first drives nanodroplets into the thrombus, while second loosens thrombus. NCMBs can be used as promising medicines carrier with rapid diffusion help design of efficient drug delivery systems.

Objectives. We sought to evaluate the impact of angiographically visible thrombus on shortand long-term clinical outcomes after percutaneous transluminal coronary angioplasty (PTCA). Background. Intracoronary thrombus is frequently seen on angiography in patients with acute ischemic coronary syndromes or complex lesion morphology, or both, and is often considered to predict a higher rate of com...

BACKGROUND AND PURPOSE Early diagnosis of cerebral venous thrombosis (CVT) is currently a major clinical challenge. We proposed a novel magnetic resonance black-blood thrombus imaging technique (MRBTI) for detection and quantification of CVT. METHODS MRBTI was performed on 23 patients with proven CVT and 24 patients with negative CVT confirmed by conventional imaging techniques. Patients were...

Abstract Thrombotic disease poses a significant threat to human health as it blocks blood vessels and leads severe symptoms. Effective treatment requires targeted therapy precise localization of the thrombus, but traditional drugs are limited in their targeting ability locate thrombus. To overcome these issues, nanoparticle capable both thrombus computed tomography (CT) imaging is developed. Ph...

The current report describes a patient with pulmonary embolism, treated unsuccessfully with heparin. Transthoracic echocardiography revealed free-floating right heart thrombus. Migrating deep vein thrombus to the right heart was suspected. Transesophageal echocardiography confirmed origin of the thrombus in the inferior cava vein. Mortality rate of mobile right heart thrombus is over 40%, there...