Received 11/22/2006; revised 2/14/2007; accepted 2/26/2007. For correspondence or reprints contact: Pei-Wen Wang, M.D., Department of Nuclear Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center. 123 Ta-Pei Road, Niao-Sung, Kaohsiung 833, Taiwan, ROC. Tel: (886)7-7317123 ext. 2627, Fax: (886)7-7317123 ext. 2631, E-mail: [email protected] The Tc-MIBI parathyroid imaging is useful for...

BACKGROUND The aim of this study is to compare the effectiveness of 131I therapy between three groups of DTC patients who received 30, 60 or 100 mCi for thyroid remnant ablation after total thyroidectomy and were postoperatively judged with low risk of cancer recurrence. METHODS The project was designed as a two-stage, prospective randomized clinical trial. In 1998-2001 in a randomized prospe...

To improve the efficacy of radioactive iodine (RAI) therapy for differentiated thyroid cancer patients, a low-iodine diet (LID) prior to the therapy is recommended. In iodine-rich areas such as Korea, however, a strict LID is very difficult to maintain. We experienced the cases of three patients showing low adherence to the LID before initial RAI therapy, and analyzed the main food source suppl...

Thyroid stunning has been reported as the temporary impairment of thyroid tissue after a 111-MBq or greater diagnostic 131I dose that decreases the final absorbed dose in ablative therapy. Concerns regarding the reality of stunning have arisen in part due to a flawed study design in prior reports. To assess whether a stunning effect has any impact on therapeutic outcomes, we compared initial tr...

HYPOTHESIS To investigate the impact of total thyroidectomy on the rate of completion thyroidectomy for incidentally found thyroid cancer in euthyroid multinodular goiter. DESIGN A randomized, prospective clinical trial. SETTING A tertiary referral center. PATIENTS Patients with euthyroid multinodular goiter without any preoperative suspicion of malignancy, history of familial thyroid can...

Postoperative ablation of functioning thyroid tissue has become established in the management of differentiated thyroid cancer as the long-term risk of recurrence and death is reduced. This beneficial effect results from the destruction of potentially malignant cells or occult multifocal disease that may occur in up to 30% of patients with papillary tumors1-4 Furthermore, the specificity of thy...

Fine needle aspiration biopsy (FNAB) is essential in the diagnosis and management of thyroid nodules. In this paper, we report a rare complication, cutaneous sinus formation, after diagnostic FNAB guided by palpation. Sixty-three-year-old female patient was admitted with the complaints of hoarseness and discharge from the anterior neck wall which were present for the last 6 months. The patient ...

(131)I is an integral component in postsurgical management of well-differentiated thyroid cancer (WDTC), which includes papillary and follicular types. (131)I is used postsurgically to either destroy remaining thyroid tissue (thyroid ablation) or to treat recurrence and metastases (radioiodine therapy). (131)I is no longer a routine diagnostic modality, but it is widely used for remnant ablatio...

the method of choice based on several reports [3–5] demonstrating equal efficacy of rhTSH compared to THW. rhTSH-assisted RAI ablative therapy is associated with similar rates of persistent disease and clinical recurrences than those observed after traditional THW preparation, at least in the short-term follow-up [6, 7] . In addition, preparation with either rhTSH or THW appears to have similar...

511 AYOUNG WOMAN with papillary thyroid cancer treated with total thyroidectomy, received an ablative dose (3000 MBq) of 131I. Thyroxine had been withdrawn for 4 weeks. A wholebody scan was performed 8 days after the ablative dose of 131I. The scan (Fig. 1) shows uptake in the thyroid bed caused by thyroid remnant, diffuse uptake in the liver, and uptake in both breasts. Post-131I therapy scans...