نتایج جستجو برای: tissue expression
تعداد نتایج: 1613066 فیلتر نتایج به سال:
The transcriptional factor OCT4 regulates pluripotency of stem cells and has an important role during oocyte growth. Whereas, its role has remained ambiguous in ovarian tissue during reproductive cycle. Therefore, this study was aimed to investigate the expression patterns of OCT4 in mouse ovaries during the normal estrous cycle. Adult National Medical Research Institute mice were classified as...
Background: The effects of electromagnetic field (EMF) on reproductive system have been of critical concern for a long time. It has been shown that the EMF can adversely affect testicular cells and tissue and decrease male fertility. The most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...
Objective: The effects of kiwifruit on the histology and cell size of adipose tissue in hyperlipidemic models have not yet been reported. Therefore, this study aimed to investigate the effect of kiwifruit on the adipose tissue cell size and activity as well as the gene expression of cholesteryl ester transfer protein (CETP) in high-fat diet (HFD...
Objective(s): The beneficial and more potent role of exercise to prevent heart apoptosis in ovariectomized rats has been known. The aim of this study was to examine the effects of swimming training on cardiac expression of Bcl-2, and Mir-133 levels and glycogen changes in the myocyte. Materials and Methods: Forty animals were separated into four groups as control, sham, ovariectomy (OVX) and o...
Introduction: This study aimed to compare the response of liver tissue BAX and BCL-2 gene expression to aerobic training with L-carnitine supplementation in rats intoxicated by Boldenone. Material and Methods: In this experimental study, 30 male Wistar rats, aged 12 weeks (weight 195±7.94 g) were randomly divided into five groups: control, no-treatment, boldenone (5 mg/kg), L-carnitine (100 mg...
Objective:The aim of the present study was to investigate the effect of 8 weeks of HIIT training and supplementation of black grape seed extract on Wnt and Β-catenin gene expression in pancreatic tissue in male rats with type 2 diabetes. Methods:In this experimental study, 40 male Wistar rats, with average weight of 250 ± 20 gr, after induction of diabetes by STZ, were randomly divided into 5 ...
Background and aims: PPARγ is one of the proteins that plays a very important role in regulating adipose tissue metabolism under physiological and metabolic conditions. Therefore, the aim of this study was to investigate the effect of three aerobic exercise methods of HIIT, HIT and MIT on the PPARγ2 gene expression in the subcutaneous adipose tissue of male Wistar rats. Methods: In this ...
Objective: Forkhead box proteins and Forkhead box transcription factor O1 (FOXO1) in particular, mediate insulin signaling pathways and glucose homeostasis. This study aimed to compare FOXO1 expression in subcutaneous adipose (SA) tissue between obese rats with and without type 2 diabetes (T2D) and its response to resistance training in T2D. Materials and Methods: 21 male wistar rats (220±20 g...
Background and Aim: One of the most common metabolic diseases is diabetes with hyperglycemic properties and endogenous insulin dysfunction. This study aimed to evaluate the effect of 10 weeks HIIT on HIF-1α gene expression in heart tissue of rats with type 2 diabetes. Methods: In this experimental study, 36 Wister rats with a mean weight of 200±58g were randomly assigned to control, diabetic,...
Background: Although testicular tissue cryopreservation could be advantageous for fertility preservation in cancerous children, the possibility of apoptosis incidence should not be ignored. Our aim was evaluation of the apoptosis incidence in mouse testicular tissue after vitrification and short-term culture. Materials and Methods: Testes of 7days old NMRI male mice were isolated, divided and d...
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