Large-scale systematic analysis of gene essentiality is an important step closer toward unraveling the complex relationship between genotypes and phenotypes. Such analysis cannot be accomplished without unbiased and accurate annotations of essential genes. In current genomic databases, most of the essential gene annotations are derived from whole-genome transposon mutagenesis (TM), the most fre...

empirical models are important tools for relating field-measured biophysical variables to remotely sensed data. regression analysis has been a popular empirical method of linking these two types of data to estimate variables such as biomass, percent vegetation canopy cover, and bare soil. this study was conducted in a semi-arid rangeland ecosystem of qazvin province, iran. this paper presents t...

Aim Previous studies have shown that the trabecular meshwork (TM) is mechanically stiffer in glaucomatous eyes as compared to normal eyes. It is believed that elevated TM stiffness increases resistance to the aqueous humor outflow, producing increased intraocular pressure (IOP). It would be advantageous to measure TM mechanical properties in vivo, as these properties are believed to play an imp...

A distributed TM model supports the TM API in a distributed system consisting of a network of nodes that communicate by message-passing links. Supporting TM in distributed systems is motivated by the difficulties of lockbased synchronization methods employed by existing distributed control-flow programming models such as RPCs. We consider Herlihy and Sun’s data-flow distributed TM model [3]. In...

Phosphorus flowing via rivers into the Baltic Sea is a major source of nutrients, and in some cases the limiting factor for the growth of algae which causes the phenomenon known as eutrophication. Remote sensing of phosphorus, here using Landsat TM-data, can help to give a better understanding of the process of eutrophication. Since Landsat TM-data is used, this could form a basis for further s...

Most mathematical models of the mammalian cochlea neglect structural longitudinal coupling. However, recent experimental data suggest that viscoelastic longitudinal coupling, in the basilar membrane (BM) and the tectorial membrane (TM), is non-negligible. In this paper, mathematical models for BM and TM longitudinal coupling are presented to determine the influence of such a coupling on the tun...

BACKGROUND Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors. Factors inducing microlith development may also, therefore, act as susceptibility factors for malignant testicular conditions. Studies to identify the mechanisms of micro...

where P (w|M) is the probability of observing w given the motif model (drawn from the frequency matrix) and P (w|B) is the probability of observing w given the background model (estimated from the sequence). All subwords w satisfying LM (w) > tM are classified as M -occurrences. There are two standard approaches to the choice of the threshold tM [1]. The first one aims at restricting the number...

CD4+ memory T cells (Tm) from rheumatoid arthritis peripheral blood (RAPB) or peripheral blood from normal donors produced IL-2, whereas fewer cells secreted IFN-gamma or IL-4 after a brief stimulation. RAPB Tm contained significantly more IFN-gamma producers than normal cells. Many rheumatoid arthritis (RA) synovial Tm produced IFN-gamma alone (40%) and fewer cells produced IL-2 or IL-4. An in...