Biofilm-related infections represent a recurrent problem in the orthopaedic setting. In recent years, great interest was directed towards the identification of novel molecules capable to interfere with pathogens adhesion and biofilm formation on implant surfaces. In this study, two stable forms of α-tocopherol, the hydrophobic acetate ester and the water-soluble phosphate ester, were tested in ...

The objective of the present investigation was to compare the antioxidant effect of different forms of Vitamin E (DL-alpha-tocopherol, Mixed Tocopherols, Ronoxan MAP and alpha-tocopherol acetate) and of topical formulations containing these active pharmaceutical ingredients, using chemiluminescence and the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays. Inhibition of the intens...

Syntrophic acetate oxidation coupled to hydrogenotrophic methanogenesis has been identified as a significant anaerobic pathway in high-temperature (55°C) oil fields (1, 2). In a paper on acetate production from oil under sulfate-reducing conditions, Callbeck et al. (3) took note of that observation, only to emphatically state that “syntrophic acetate oxidation coupled to hydrogenotrophic methan...

1. 7- and 12-Methylbenz[a]anthracene were converted by rat-liver homogenates into the corresponding hydroxymethyl derivatives, products that are probably the 8,9-dihydro-8,9-dihydroxy and the 5,6-dihydro-5,6-dihydroxy derivatives, and a number of phenolic products. 2. Both hydrocarbons were converted into glutathione conjugates; that from 7-methylbenz[a]anthracene was also formed, together with...

The title compounds, [(1R,3R,4R,5R,6S)-4,5-bis-(acet-yloxy)-7-oxo-2-oxabi-cyclo[4.2.0]octan-3-yl]methyl acetate, C14H18O8, (I), [(1S,4R,5S,6R)-5-acet-yloxy-7-hy-droxy-imino-2-oxobi-cyclo-[4.2.0]octan-4-yl acetate, C11H15NO6, (II), and [(3aR,5R,6R,7R,7aS)-6,7-bis-(acet-yloxy)-2-oxo-octa-hydro-pyrano[3,2-b]pyrrol-5-yl]methyl acetate, C14H19NO8, (III), are stable bicyclic carbohydrate derivatives....

I. Two experimental groups, each of thirteen boarding schoolboys, were given either 400 mg a-tocopheryl acetate or placeboes daily in addition to their normal diet during training in swimming and various athletic activities over a period of 6 weeks. Evaluation of the experimental treatments was made from tests of anthropometric status, cardiorespiratory efficiency and motor fitness and performa...

In the title compound, C(27)H(24)O(14), also known as 2,3-di-acetoxy-5-[(2RS,3RS)-3,5,7-triacetoxy-4-oxochromen-2-yl]phenyl acetate, the heterocyclic ring adopts a distorted half-chair conformation, with two C atoms displaced by 0.1775 (16) and -0.5950 (16) Å from the mean plane of the other four atoms. The dihedral angle between the aromatic rings is 57.81 (8)°. In the crystal, the mol-ecules ...

The title compound, C(34)H(54)O(5), was synthesized by the reaction of ursolic acid with ethyl chloro-acetate in the presence of DMA. All six-membered rings of the penta-cyclic triterpene skeleton adopt chair conformations. In the crystal structure, mol-ecules are linked by inter-molecular O-H⋯O hydrogen-bond inter-actions, forming zigzag chains along the c axis.

A total of 126 gilts and sows (PIC 1050) and their litters were used to determine the effects of dietary vitamin E concentration and source on sow plasma, milk, and pig concentrations of α-tocopherol. Additionally, we estimated the bioavailability of D-α-tocopheryl acetate (D-α-TAc) relative to DL-α-tocopheryl acetate (DL-α-TAc) when fed in diets containing dried distillers grains with solubles...