Acrolcin-fixed, polyester wax-cmbcddcd tissue sections showed excellent preservation of light microscopic architecture and, when stained with toluidinc blue, intense color contrast between DNA, which stained orthochromatically, and RNA, which stained metachromatically. This method has practical value for differentiating DNA from RNA in the same section. The color c~)ntrast was impaired by subst...

Acrolcin-fixed, polyester wax-cmbcddcd tissue sections showed excellent preservation of light microscopic architecture and, when stained with toluidinc blue, intense color contrast between DNA, which stained orthochromatically, and RNA, which stained metachromatically. This method has practical value for differentiating DNA from RNA in the same section. The color c~)ntrast was impaired by subst...

Acrolcin-fixed, polyester wax-cmbcddcd tissue sections showed excellent preservation of light microscopic architecture and, when stained with toluidinc blue, intense color contrast between DNA, which stained orthochromatically, and RNA, which stained metachromatically. This method has practical value for differentiating DNA from RNA in the same section. The color c~)ntrast was impaired by subst...

Acrolcin-fixed, polyester wax-cmbcddcd tissue sections showed excellent preservation of light microscopic architecture and, when stained with toluidinc blue, intense color contrast between DNA, which stained orthochromatically, and RNA, which stained metachromatically. This method has practical value for differentiating DNA from RNA in the same section. The color c~)ntrast was impaired by subst...

OBJECTIVE To use toluidine blue intra-operatively to identify tumour involved margins after the removal of oral cavity squamous cell carcinoma, and to compare the findings with those of final histopathology. METHODS The study was conducted at the Aga Khan University Hospital from December 1, 2009, to March 14, 2010, and comprised 56 consecutive patients with biopsy-proven squamous cell carcin...

BACKGROUND Early detection holds the key to an effective control of cancers in general and of oral cancers in particular. However, screening procedures for oral cancer are not straightforward due to procedural requirements as well as feasibility issues, especially in resource-limited countries. METHODS We conducted a cross-sectional study to compare the performance of chemiluminescence, tolui...

Objective: The incidence of oral cancer worldwide varies 2-18% and in India 0.1 to 13.5%. Early evaluation of oral precancerous lesions can have dramatic effect on oral cancer mortality rate. Among the premalignant stage, leukoplakia is the most commonly encountered clinical lesion and epithelial dysplasia is most important predictive factor. The objective of this paper is to compare the effica...