In human enamel, the enamel rods do not run straight in most regions. Instead, they obtain an undulated path. The diameter of the enamel rods remains constant all the way, and a wavy pattern is necessary to produce the volume of the enamel mantle. It is not understood, how this undulated migration of ameloblasts is created. Considerations are presented to explain causal interdependencies betwee...

Tooth enamel contains relics of its formation process, in the form of microstructures, which indicate the incremental way in which it forms during enamel formation on teeth (). These microstructures, called cross-striations and striae of Retzius, develop as enamel-forming cells called ameloblasts, which cyclically deposit enamel on developing teeth in accordance with two different biological cl...

Dental enamel thickness continues to feature prominently in anthropological studies of ape and human evolution, as well as studies of preventative oral care and treatment. Traditional studies of enamel thickness require physical sectioning of teeth for linear and scaled measurements. Recent applications of microtomographic imaging allow scientists to employ larger and more diverse samples, incl...

AIM OF THE STUDY Chemotherapeutic treatment in children and adolescents carries a risk of congenital tooth disorders and dentinoma. Study objective is to assess the correlation between tooth abnormalities, early complications of multidrug chemotherapy, and chemotherapeutics used in different antineoplastic therapies in children and adolescents. MATERIAL AND METHODS Enamel defects (development...

The enamel organ engaged in enamel matrix formation in tooth germs comprises four different cell types: the ameloblasts, the cells of the stratum intermedium, stellate reticulum, and the outer enamel epithelium, each characterized by distinct structural features. In ordinary primary cultures of tooth-derived cells, these cells generally become flat in profile and hardly regain their original pr...

Epithelial morphogenesis generates the shape of the tooth crown. This is driven by patterned differentiation of cells into enamel knots, root-forming cervical loops and enamel-forming ameloblasts. Enamel knots are signaling centers that define the positions of cusp tips in a tooth by instructing the adjacent epithelium to fold and proliferate. Here, we show that the forkhead-box transcription f...

OBJECTIVES Bond strength of composite resin to enamel and dentin of primary teeth is lower than that to permanent teeth; therefore, it may compromise the adhesive bonding. New methods, such as laser application have been recently introduced for tooth preparation. The purpose of this study was to evaluate the effect of tooth preparation with bur and Er:YAG laser on shear bond strength of composi...

DOURING the process of studying the physical damage and traumatic effects of various instruments on tooth structure, it became apparent that some consideration should be given to the Hunter-Schreger band formation as it exists in enamel structure. When examined by reflected light, these bands appear as alternating light and dark areas in the enamel portion of a longitudinal groundtooth section,...

The final shape of the molar tooth crown is thought to be regulated by the transient epithelial signaling centers in the cusp tips, the secondary enamel knots (SEKs), which are believed to disappear after initiation of the cusp growth. We investigated the developmental fate of the signaling center using the recently characterized Slit1 enamel knot marker as a lineage tracer during morphogenesis...