Oxidative damage has been suggested to be a contributing factor in the development to diabetic nephropathy (DN). Recently, there has been evidence that pentoxifylline (PTX) has free radical-scavenging properties; thus, its anti-inflammatory and renoprotective effects may be related to a reduction in reactive oxygen species production. It is likely that the pharmacological effects of PTX include...

background and objectives: dairy companies always try to increase the quantity and quality of milk production. according to the positive impact of different plants on milk production of cattle, this study was carried out to standardize a galactogogue herbal mixture based on its total phenol and flavonol contents and antioxidant activity.  methods: a mixture of galega officinalis l. and nigella ...

Purpose: to evaluate the topical use effect of angiotensin-converting enzyme (ACE) inhibitor (iACE) Enalaprilat in eye drops on blood flow volume, hypoxia degree, ACE activity, and total antioxidant activity (TAA) aqueous humor rabbits with experimental ocular ischemia. Material methods . Transient ischemia 30 Chinchilla was induced by subconjunctivally injecting 0.2 ml 1 % Phenylephrine. Ocula...

BACKGROUND Severe Acute Liver Failure (ALF) is a life-threatening clinical syndrome characterized by hepatocyte necrosis, loss of hepatic architecture, and impairment of liver functions. One of the main causes of ALF is hepatotoxicity from chemical agents, which damage hepatocytes and result in increase of reactive oxygen species. The vitamin E isoform is the one with the strongest biological a...

Background: There are many reports regarding to effects of Granulocyte colony-stimulating factor (G-CSF) and stem cell factor (SCF)alone in liver repair .But conflicting data have been reported regarding the role of growth factors such as G-CSF and SCF in the liver regeneration system. Also, there is not such data regarding to effects of co-administration both of G-CSF and SCF in the liver dama...

in this study, we have examined the antioxidant activity and total phenolic content of different extracts (including water, methanol, water : methanol and acetone) of nerium oleander l. grown in the north of iran by employing various in-vitro assay, i.e. dpph free radical scavenging, reducing power and total antioxidant capacity through the mo (vi) reduction. the extracts showed different level...

Objective:Testicle torsion/detorsion cause ischemia. Rapamycin has immune suppressive and antioxidant defense mechanisms. Nucleolar-organizing regions(NORs) are loops of ribosomal DNA. Methods: To evaluate mean AgNOR number total area/total nuclear area(TAA/TNA) ratio the relation between these proteins rapamycin in Torsion/Detorsion process testes. The six groups as control, sham, early late t...

in the present study, we have reported the total phenolic content, total flavonoid content, antioxidant and antimicrobial activity of aerial parts of salvia leriifolia extracts and fractions. methanolic, n-hexane, chloroform, and ethyl acetate extracts were screened to analysis their antioxidant activities by four complementary test systems, namely dpph free radical scavenging activity (rsa), t...

sour cherry and orange juice were successfully cryoconcentrated. novel clarification (electro-flotation and ultra-filtration) improved cryconcentration efficiency. ef-uf clarified sour cherry and orange juices were cryoconcentrated in three stages up to 34.52±0.14, 44.42±0.19, 52.44±0.13 and 28.43±0.16, 40.51±0.15, and 45.42±0.19° brix at -10˚c respectively. duncan's multiple range test was use...

Currently, there is increased interest in finding appropriate food-grade green extraction systems capable of extracting these bioactive compounds from dietary mushrooms for applications various food, pharmacological, or nutraceutical formulations. Herein, we evaluated a modified Swiss water process (SWP) method using alkaline and acidic pH at low high temperature under pressurized conditions as...