The purpose of this study was to determine the presence and extent of pulmonary elimination for 5-fluorouracil (FUra). A secondary aim was to characterize the relative importance of the liver, gastrointestinal tract, splanchnic region, and lungs toward the overall elimination of FUra. A total of 10 mixed-breed male and female dogs were used in these acute studies in which FUra was administered ...

BACKGROUND The accumulation of larger and protein-bound toxins is involved in the uraemic syndrome but their elimination by dialysis therapy remains difficult. In the present study, the impact of the albumin permeability of recently introduced advanced high-flux dialysis membranes on the removal of such substances was tested in haemodialysis and online post-dilution haemodiafiltration. METHOD...

The main objective of endodontic treatment is the total removal any necrotic tissues and microorganisms along with their byproducts found within infected root canal to treat prevent recolonization these micrbad oorganisms. To date, no known irrigant has a 100% elimination rate on microorganisms, many combinations irrigates have been suggested, care must be taken mixing interaction side effects....

We examined the hypothesis that rate of elimination of nicotine affects nicotine intake during cigarette smoking. Elimination rate was altered by administering ammonium chloride or sodium bicarbonate throughout the day. Nicotine intake during unrestricted cigarette smoking was measured using metabolic clearance data obtained after i.v. nicotine infusion together with blood and urinary nicotine ...

We prove a central limit theorem for the nite dimensional marginals of the Gibbs distribution of the macroscopicòverlap'-parameters in the Hoppeld model in the case where the number of random`patterns', M, as a function of the system size N satisses lim N"1 M(N)=N = 0, without any assumptions on the speed of convergence. The covariance matrix of the limiting gaussian distributions is diagonal a...

In this paper we study the problem of optimizing the distortion compensation parameter for the Scalar Costa Scheme, which is a practical version of the class of Distortion Compensated Dither Modulation schemes. In the literature, a number of results are known for finding the value of the distortion compensation parameter that maximizes the capacity of the watermarking channel. Instead, in this ...

the pharmacokinetic parameters of ceftazidime, a third generation cephalosporin, were investigated in six buffalo calves after single intravenous (iv) and intramuscular (im) administration at a dose rate of 10 mg/kg body weight. ceftazidime concentrations in plasma and urine were determined by microbiological assay. ceftazidime disposition was best fitted by a two-compartmental and a one-compar...