Cardiac perforation after pacemaker or implantable cardioverter-defibrillator (ICD) implantation is an infrequent complication. The reported rates of perforation are 0.1-0.8% after pacemaker implantation and 0.6-5.2% after ICD implantation (Khan et al., 2005; Mahapatra et al., 2005). From 1994 to 2009, total 1026 permanent pacemakers and ICDs were implanted in my lab, and two cases (0.2%) devel...

BACKGROUND The use of ulcerogenic drugs is the only well documented risk factor for peptic ulcer perforation, but accounts for only a quarter of the events. Smoking is a well known risk factor for uncomplicated ulcer disease, and patients with ulcer bleeding have increased death rates from smoking related disorders. AIM To assess the role of smoking in ulcer perforation. SUBJECTS A total of...

The 4to 6-year outcome of orthograde retreatment was assessed for Phases I and II of the Toronto Study. In total, 523 teeth in 444 patients were retreated. With 395 teeth lost to follow-up and 25 extracted, 103 teeth (34% recall) were examined by two independent, blinded, calibrated examiners for outcome: “healed” (absence of apical periodontitis, signs, or symptoms) or “diseased” (presence of ...

The 4- to 6-year outcome of orthograde retreatment was assessed for Phases I and II of the Toronto Study. In total, 523 teeth in 444 patients were retreated. With 395 teeth lost to follow-up and 25 extracted, 103 teeth (34% recall) were examined by two independent, blinded, calibrated examiners for outcome: "healed" (absence of apical periodontitis, signs, or symptoms) or "diseased" (presence o...

AIM To investigate predictors of perforation after endoscopic resection (ER) for duodenal neoplasms without a papillary portion. METHODS This was a single-center, retrospective, cohort study conducted between April 2003 and September 2014. A total of 54 patients (59 lesions) underwent endoscopic mucosal resection (EMR) (n = 36) and endoscopic submucosal dissection (ESD) (n = 23). Clinical fea...

PMs8 estiMating the iMPact of exPanDing access to celecoxib for osteoarthritis Patients in china Wang B.C.M.1, Xie X.P.2, Furnback W.1 1Alliance Life Sciences, Somerset, NJ, USA, 2Pfizer Inc., Beijing, China Objectives: Currently in China, celecoxib is prescribed to patients with gastrointestinal bleeding or perforation history. The aim of this study was to model the effect of expanding access ...

BACKGROUND/AIMS Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is useful for the pathological diagnosis of pancreatic masses, but patients are susceptible to severe bleeding and perforation. Because the incidence and severity of these complications have not been fully evaluated. METHODS We aimed to evaluate severe bleeding and perforation after EUS-FNA for pancreatic masses usi...

Arare case of ileal perforation, as a fatal initial presentation of total colonic aganglionosis (TCA) in infancy is reported. A 10-week-old boy, was brought to the emergency department with symptoms of complicated intestinal obstruction. He looked ill, was lethargic, markedly dehydrated and had a severely distended abdomen. An abdominal X-ray revealed multiple air fluid levels seen in a distend...

A 45-year-old woman with type 1 diabetes and chronic renal failure on dialysis underwent simultaneous pancreas-kidney transplantation from a brain dead donor. On postoperative day 15, acute generalized peritonitis was diagnosed and emergency laparotomy was performed. Perforation of the donor duodenum was found, which had apparently resulted from duodenal compression by the tip of the intestinal...

We present here a case of uterine perforation following manual removal of the placenta during the third stage of normal labor. Total abdominal hysterectomy was performed, and the 4x3-cm perforation of the uterus and placenta accreta were confirmed. In this case, the round ligament covering the hematoma prevented bleeding into the peritoneal cavity and peritonitis. Manual removal of the placenta...