An investigation was carried out to evaluate the relative toxicity of selected newer insecticides viz., deltamethrin, spinosad, abamectin and emamectin benzoate in comparision with the organophosporus insecticide malathion to the maize weevil, Sitophilus zeamais Motschulsky, in an attempt to find out a safer and effective seed protectant. The LC50 values based on bioassay studies indicated that...

The objective of this study was the sediment quality assessment of Ganga River at Kanpur city where effluents from tannery industries are discharged. Sediment samples from upstream and downstream area were collected and analyzed for trace metals and toxicity bioassay. Among various trace metals examined Cr in downstream sediment was 30-fold higher than in upstream sediment and its concentration...

The MicrotoxTM bioassay and polarographic techniques were used together to identify specific oxidation states and toxicity of metals. The bioassay is based on light reduction by bioluminescent bacteria upon exposure to toxicants. In polarography, a mercury drop substrate’s potential is changed, and the substance of interest is electrochemically reduced. Reduction current is proportional to its ...

Peptaibols are small linear fungal peptides which are produced in the marine environment. They exhibit neurotoxicity by forming pores in neuronal membranes. This work describes their combine effect with domoic acid, a neurotoxic phycotoxin, on Diptera larvae. The Acute toxicity bioassay on this biological model was tested with a panel of different toxins (microbial, algal or fungal). It allowed...

BACKGROUND Improved chemical hazard management such as REACH policy objective as well as drug ADMETOX prediction, while limiting the extent of animal testing, requires the development of increasingly high throughput as well as highly pertinent in vitro toxicity assays. METHODOLOGY This report describes a new in vitro method for toxicity testing, combining cell-based assays in nanodrop Cell-on...

A bioassay that used postexposure feeding depression in Daphnia magna Straus as an endpoint previously had been developed under laboratory conditions. Laboratory studies revealed that this was a sensitive, robust endpoint, which could potentially be used in an in situ bioassay. This study adapted the laboratory bioassay for use in the field and deployed D. magna in situ at four known or suspect...

Background: Faba bean toxicity (favism) is a common condition observed in our region. Objective: To develop a short and simple technique involving the use of riboflavin-deficient rats to test in vivo faba bean toxicity. Methods/Results: Sprague Dawley rats were maintained on a riboflavin-deficient diet and their vitamin B2 status was monitored by the assay of erythrocyte glutathione reductase (...

BACKGROUND The EU member countries are currently implementing the Water Framework Directive to promote better water quality and overview of their waters. The directive recommends the usage of bioavailability tools, such as biotic ligand models (BLM), for setting environmental quality standards (EQS) for metals. These models are mainly calibrated towards a water chemistry found in the south cent...