The aim of this study is to evaluate the importance toxicological analysis in acute intoxications by pesticides through experience laboratory Poison Control and Pharmacovigilance Center Morocco (CAPM). This a retrospective from January 2014 September 2020, concerning suspected poisoning cases. cholinesterase activity was measured whole blood chromatographic analyzes (GC-MS LC-MS-MS) were conduc...

It has been known for 50 years or longer that much disease is caused by reactive oxygen species (ROS). At an international meeting of the World Health Organization in the mid-1960s, the distinguished Russian toxicologist, Professor Sanojki, presented a major treatise on the ‘rusting diseases’, a phrase not understood by many American and European delegates, but intended to mean diseases attribu...

Leading QSAR models provide supporting documentation in addition to a predicted toxicological value. Such information enables the toxicologist to explore the properties of chemical substances as well as to review and to increase the reliability of toxicity predictions. This article focuses on the use of this information in practice. We explore the supporting documentation provided by the EPISui...

Cardiovascular drugs are a common cause of poisoning, and toxic bradycardias can be refractory to standard ACLS protocols. It is important to consider appropriate antidotes and adjunctive therapies in the care of the poisoned patient in order to maximize outcomes. While rigorous studies are lacking in regards to treatment of toxic bradycardias, there are small studies and case reports to help g...

The performance of trained medicolegal investigators was evaluated in 100 consecutive drug deaths, which occurred from January 1978 to May 1980 in St. Louis City and County. Carbon monoxide deaths were excluded from the study. The toxic agent responsible for death, as indicated by scene investigators and the decedent's drug history, was compared to the actual toxicology laboratory findings. In ...

These days young people use internet as a source of information. Internet offers knowledge that can be used not only for school education but also to obtain information about usage and effects of psychoactive substances. Recent research shows that young people more often use internet websites and chat rooms to exchange knowledge and experience with chemicals and everyday products used as intoxi...

when one searches in vain for the place where one can buy the reagent. In certain sections, such an approach limits the book's usefulness to the technician's level. Perhaps the most unfortunate decision the author has made has been to limit the methods described to purely chemical ones. In many instances (e.g., epinephrine), where physical methods (such as spectrophotometry) have been applied w...

“CSI” – CRIME SCENE INVESTIGATION! The very words conjure up a picture of murder, mystery, police officers, and poison analysis. Few would normally associate such activities—and all else that is part of modern forensic science—with contemporary veterinary practice. Nothing, however, could be further from the truth. Forensic veterinary medicine is here to stay! So what is exactly is “forensic ve...