The immunopathogenesis of toxoplasmosis during pregnancy is not completely understood. This paper will try to discuss the most frequently asked questions about the immunopathogeny of congenital toxoplasmosis: differential virulence of Toxoplasma isolates, genetic susceptibility to infection, facilitation of placental transfer, models of congenital toxoplasmosis, and transmission in seropositive...

• Toxoplasmosis is one of the most globally significant zoonotic diseases. Public health measures are critical but not sufficient to control toxoplasmosis. Several new anti- Toxoplasma chemotherapeutic targets have been identified. New immunotherapies and vaccines for toxoplasmosis promising experimental. Nanotechnologies could improve diagnosis delivery agents. caused by gondii, an apicomplexa...

Toxoplasmosis was the most common cause of primary retinochoroiditis. The majority of cases of ocular toxoplasmosis were congenital. However, cases of acquired ocular toxoplasmosis have been reported. The clinical manifestations of congenital ocular toxoplasmosis were choroidal coloboma, strabismus, nystagmus, ptosis, microphthalmia, cataract and enophthalmia. The purpose of this study was to d...

The diagnostic value of toxoplasma serology in ocular disease was evaluated in the following groups of patients: (I) uveitis cases of various causes (n = 291); (II) consecutive posterior and panuveitis patients (n = 60); (III) patients with definite congenital and ocular toxoplasmosis (n = 8); (IV) cases of clinical ocular toxoplasmosis (n = 25); and control patients with uveitis of non-toxopla...

Toxoplasmosis is a worldwide zoonosis that generally produces an asymptomatic infection. In some cases, however, toxoplasmosis infection can lead to ocular damage. The immune system has a crucial role in both the course of the infection and in the evolution of toxoplasmosis disease. In particular, IFN-gamma plays an important role in resistance to toxoplasmosis. Polymorphisms in genes encoding ...

Feline enteric coronavirus (FECV) infects enterocytes and causes inflammation of the intestinal mucosa in young cats, resulting diarrhea. In adult cats infection is usually asymptomatic, but constant circulation FECV feline population increases likelihood mutation, as a result which about 5-10% infected develop virulent strain virus that lethal infectious peritonitis – FIP. The purpose this stu...

Manuls or Pallas' cats (Felis manul, syn. Otocolobus manul) are endangered wild cats from Central Asia kept and bred in many zoos. Despite good breeding success young cats frequently die from acute toxoplasmosis. From 1998 to 2002, a breeding pair in the Schönbrunn Zoo in Vienna, Austria, gave birth to 24 kittens; 58 % of kittens died between the 2nd and the 14th week of life, mostly due to acu...

The latex agglutination test for toxoplasmosis was performed on 690 blood samples collected from the Veterans and Bang Bua Thong Hospitals in Bangkok. Blood samples were collected in the first- and the third-trimester from pregnant women and from the cord blood. The seroprevalence of toxoplasmosis in the first trimester was 13.14%, 13.60%; in the third trimester was 12.21%, 9.43% and in the cor...

BACKGROUND Ocular toxoplasmosis is a potentially blinding cause of posterior uveitis. Retinal detachment is rare complication of ocular toxoplasmosis. AIM To report the clinical course and prognosis of retinal breaks and detachments occurring in patients with ocular toxoplasmosis. PATIENTS AND METHODS This study was a retrospective, non-comparative case series of five patients with ocular t...

Ocular toxoplasmosis is a common vision-threatening disease in Indonesia. Diagnosis of this disease is based on characteristic ophthalmoscopic appearances and laboratory findings. Between 1985 and 1989, the authors retrospectively evaluated 41 children under 12 years of age. Thirteen cases had retinal lesions suspected to be toxoplasmosis but the laboratory findings were negative. The remaining...