BACKGROUND Shikonin is a component of Chinese herbal medicine. The aim of this study was to investigate the effects of shikonin on cell migration of papillary thyroid cancer cells of the TPC-1 cell line in vitro and expression levels of the phosphate and tensin homolog deleted on chromosome 10 (PTEN) and DNA methyltransferase 1 (DNMT1) genes. MATERIAL AND METHODS The Cell Counting Kit-8 (CCK-8)...

There has been very little empirical analysis of any real production database workloads. Although the Transaction Processing Performance Council benchmarks C (TPC-C) and D (TPC-D) have become the standard benchmarks for on-line transaction processing and decision support systems, respectively, there has not been any major effort to systematically analyze their workload characteristics, especial...

Euphorbia tirucalli (E. tirucalli) is now widely distributed around the world and is well known as a source of traditional medicine in many countries. This study aimed to utilise response surface methodology (RSM) to optimise ultrasonic-assisted extraction (UAE) conditions for total phenolic compounds (TPC) and antioxidant capacity from E. tirucalli leaf. The results showed that ultrasonic temp...

A large volume Time Projection Chamber (TPC) is being considered for the central charged particle tracker for the detector for the proposed International Linear Col-lider (ILC). To meet the ILC-TPC spatial resolution challenge of ∼ 100 µm with a manageable number of readout pads and channels of electronics, Micro Pattern Gas Detectors (MPGD) are being developed which could use pads comparable i...

Abstract It is known that in wireless packet communications the so called capture effect can be expected if the received signal is given certain power variations. Previously we have proposed a random TPC method. In this method, since received signal power variations are intentionally given in order to obtain capture effect, the link capacity is much larger than that of the conventional fast and...

Cereal grains are generally subjected to thermal treatment before consumption. However, few data are available on total phenolic content (TPC), degree of starch gelatinization, phenolic acids, and antioxidant capacity of extruded whole grains based on trolox equivalent antioxidant capacity (TEAC), DPPH radical scavenging activity, and ferric reducing antioxidant potential (FRAP). Four whole gra...

As improvements in processor performance continue to far outpace improvements in storage performance, I/O is increasingly the bottleneck in computer systems, especially in large database systems that manage huge amounts of data. The key to achieving good I/O performance is to thoroughly understand its characteristics. In this paper, we present a comprehensive analysis of the logical I/O referen...

A graph is said to be total-colored if all the edges and the vertices of the graph is colored. A path in a total-colored graph is a total proper path if (i) any two adjacent edges on the path differ in color, (ii) any two internal adjacent vertices on the path differ in color, and (iii) any internal vertex of the path differs in color from its incident edges on the path. A total-colored graph i...

The Transaction Processing Performance Council (TPC) is completing development of TPC-DS, a new generation industry standard decision support benchmark. The TPC-DS benchmark, first introduced in the “The Making of TPC-DS” [9] paper at the 32 International Conference on Very Large Data Bases (VLDB), has now entered the TPC’s “Formal Review” phase for new benchmarks; companies and researchers ali...

PURPOSE New treatments with novel mechanisms of action and non-overlapping toxicities are needed for patients with metastatic breast cancer. Etirinotecan pegol (EP) is a long-acting topoisomerase-I inhibitor with a unique toxicity profile. The randomized phase 3 BEACON study that compared EP to treatment of physician's choice (TPC) demonstrated its clinical activity. We now present detailed saf...