In analogy to the ow of uids, it is expected that the aggregate density and the velocity of vehicles in a section of a freeway adequately describe the tra c ow dynamics. The conservation of mass equation together with the aggregation of the vehicle following dynamics of controlled vehicles describes the evolution of the tra c density and the aggregate speed of a tra c ow. There are two kinds of...

Assume T is superstable and small. Using the multiplicity rankM we find locally modular types in the same manner as U -rank considerations yield regular types. We define local versions of M-rank, which also yield meager types. 0. Introduction. Throughout, T is superstable, small, and we work in C = C. In [Ne1] we defined the multiplicity rank M and proved that M has additivity properties simila...

Caenorhabditis elegans and Caenorhabditis briggsae are both self-fertile hermaphroditic nematodes that evolved independently from male/female ancestors. In C. elegans, FEM-1, FEM-2, and FEM-3 specify male fates by promoting proteolysis of the male-repressing transcription factor, TRA-1. Phenotypes of tra-1 and fem mutants are consistent with this simple linear model in the soma, but not in the ...

The Available Bit Rate (ABR) service has been shown to enable persistent, greedy data sources to e ciently utilize ATM network resources. However, the throughput for bursty TCP over ABR data tra c in the presence of interfering tra c may not be as good as for persistent ABR sources without interfering tra c. This paper shows that in a comparison of rate based ABR schemes (EPRCA and ERICA) and a...

All-trans retinoic acid (tRA)-induced differentiation in NB4 cells, a cell line derived from an acute promyelocytic leukemia patient with t(15;17) translocation, is markedly facilitated by sodium butyrate (NaB), a histone deacetylase inhibitor (HDACI), or by hexamethylene bisacetamide (HMBA), a non-HDACI tRA-differentiation inducer, as determined by nitroblue tetrazolium reduction. The tRA-indu...

Sex determination in Drosophila melanogaster is under the control of the X chromosome:autosome ratio and at least four major regulatory genes: transformer (tra), transformer-2 (tra-2), doublesex (dsx) and intersex (ix). Attention is focused here on the roles of these four loci in sex determination. By examining the sexual phenotype of clones of homozygous mutant cells produced by mitotic recomb...

TRA-8, a monoclonal antibody to death receptor 5 induces apoptosis in various cancer cells; however, the degree of sensitivity varies from highly sensitive to resistant. We have previously shown that resistance to TRA-8 can be reversed by using chemotherapeutic agents, but the mechanism underlying this sensitization was not fully understood. Here, we examined the combination of TRA-8 with doxor...

TRAIL induces apoptosis in a variety of tumorigenic and transformed cell lines, but not in many normal cells. Recent studies have demonstrated that death receptor 5 (DR5), one of the two death receptors bound by TRAIL, showed expression in most malignantly transformed cells. This study evaluated effects of a monoclonal antibody (TRA-8) to human death receptor 5, combined with ionizing radiation...

The conjugative multiple antibiotic resistance plasmid pIP501 can be transferred and stably maintained in a variety of Gram-positive genera, including multicellular Streptomyces lividans, as well as in Gram-negative Escherichia coli. The 15 putative pIP501 transfer (tra) genes are organized in an operon-like structure terminating in a strong transcriptional terminator. This paper reports co-tra...

We study the performance of various strategies for scheduling a combined load of unicast and multicast tra c in a broadcast WDM network. The performance measure of interest is schedule length, which directly a ects both aggregate network throughput and average packet delay. Three di erent scheduling strategies are presented, namely: separate scheduling of unicast and multicast tra c, treating m...