OBJECTIVE To investigate whether trabecular and cortical bone structure differ between patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA). So far, no study has performed a detailed comparative analysis of bone structure in patients with RA and PsA. METHODS 110 patients (60 RA, 50 PsA) received high-resolution peripheral quantitative CT of the distal radius. Demographic and ...

The aim of this study was to measure the bone mineral density specific regions maxilla, mandible, and first cervical vertebra using Hounsfield unit trabecular microstructure pattern analysis compare two methods. In study, cone-beam computed tomography (CBCT) images were obtained from 58 patients. Trabecular thickness, number, separation, volume fraction measured in 484 for parameters grayscale ...

The inelastic pressure dependent compressive behaviour of bovine trabecular bone is investigated through experimental and computational analysis. Two loading configurations are implemented, uniaxial and confined compression, providing two distinct loading paths in the von Mises-pressure stress plane. Experimental results reveal distinctive yielding followed by a constant nominal stress plateau ...

Trabecular plates play an important role in determining elastic moduli of trabecular bone. However, the relative contribution of trabecular plates and rods to strength behavior is still not clear. In this study, individual trabeculae segmentation (ITS) and nonlinear finite element (FE) analyses were used to evaluate the roles of trabecular types and orientations in the failure initiation and pr...

Understanding the mechanically-mediated response of trabecular bone to locomotion-specific loading patterns would be of great benefit to comparative mammalian evolutionary morphology. Unfortunately, assessments of the correspondence between individual trabecular bone features and inferred behavior patterns have failed to reveal a strong locomotion-specific signal. This study assesses the relati...

Previous studies have shown that the mechanical properties of trabecular bone are determined by bone volume fraction (BV/TV) and microarchitecture. The purpose of this study was to explore other possible determinants of the mechanical properties of vertebral trabecular bone, namely collagen cross-link content, microdamage, and mineralization. Trabecular bone cores were collected from human L2 v...

PO Box 513, 5600 MB Eindhoven, The Netherlands Introduction Osteoporotic fractures mainly occur at sites with relatively large amounts of trabecular bone. The devastating effects of such fractures can be prevented with accurate predictions of trabecular bone strength. Micro-finite element (μFE) models have been successfully used to study and predict trabecular bone elastic and yield properties....

Initiated and motivated by clinical and scientific problems such as age-related bone fracture, prosthetic loosening, bone remodeling, and degenerative bone diseases, much significant research on the properties of trabecular bone has been carried out over the last two decades. This work has mainly focused on the central vertebral trabecular bone, while little is known about age-related changes i...

OBJECTIVE The objective of this study was to evaluate the relationship between the trabecular bone microarchitecture and cortical bone morphology by using micro-computed tomography (micro-CT) and dental cone-beam computed tomography (dental CT). MATERIALS AND METHODS Sixteen femurs and eight fifth lumbar vertebrae were collected from eight male Sprague Dawley rats. Four trabecular bone microa...

High-resolution peripheral quantitative computed tomography (HR-pQCT) is a newly developed in vivo clinical imaging modality. It can assess the 3D microstructure of cortical and trabecular bone at the distal radius and tibia and is suitable as an input for microstructural finite element (microFE) analysis to evaluate bone's mechanical competence. In order for microstructural and image-based mic...