Background Most patients with large vessel occlusion (LVO) stroke need to be transferred to receive thrombectomy. To save time, the decision to transfer often relies on clinical scales as a surrogate for LVO rather than imaging. However, clinical scales have been associated with high levels of diagnostic error. The aim of this study is to define the susceptibility to overdiagnosis of our curren...

BACKGROUND AND PURPOSE Peripheral immune cell infiltration contributes to neural injury after ischemic stroke. However, in contrast to lymphocytes and neutrophils, the role of different monocyte/macrophage subsets remains to be clarified. Therefore, we evaluated the effects of selective and unselective monocyte/macrophage depletion and proinflammatory (M1-) and anti-inflammatory (M2-) macrophag...

Objectives: Fear of falling (FOF) is a common complication after stroke affecting gait and balance performance in individuals with a history of stroke. The current study aimed at determining the influence of the level of FOF on gait and balance performance after chronic stroke. Methods: A total of 76 persons with chronic stroke (including 41 women), who had no cognitive impairment and could wa...

BACKGROUND AND PURPOSE Many patients are transferred to comprehensive stroke centers for advanced acute ischemic stroke care, especially after intravenous tissue plasminogen activator. We sought to determine differences in the baseline characteristics and outcomes between patients with acute ischemic stroke presenting directly to our academic stroke center's front door versus transfers-in from ...

background: temporal variation of stroke onset is suggested in some studies contained somewhat varieties. it is proposed that some predisposing changes occur in some ascertained times consequently resulted in stroke occurrence in some special times. objective: to determine the circadian and circaseptan variation of stroke onset. materials and methods: this cross sectional study was conducted fr...

Objective: To evaluate low-molecular-weight (LMW) DNA as possible prognostic biomarker in acute ischemic and hemorrhagic stroke. Methods:  LMW DNA samples were isolated from plasma and cerebrospinal fluid by phenol deproteinization, analyzed by gradient polyacrylamide electrophoresis and quantified by spectrophotometry. Results: Two common types of the stroke, ischemic and hemorrhagic, differ...

Introduction: TRPV1 is a non-selective cation channel with high permeability to calcium ions, and is also involved in the development of neurogenic and inflammatory pain. The increase in intracellular calcium plays a role in worsening of stroke. In the present study we investigated the effect of (AMG9810) TRPV1 receptor antagonist on stroke outcome in the permanent middle cerebral artery occlus...

stroke scales can be classified as clinicometric scales and functional impairment, handicap scales. all studies describing stroke scales were reviewed by internet searching engines with the final search performed on january 1, 2013. the following string of keywords was entered into search engines; stroke, scale, score and disability. despite advantages of modified national institute of health s...

stroke is the third cause of death in the world after the cancer and cardiovascular disease. . it has been shown that stroke in northeast of iran occurs approximately one decade earlier than in western countries. reasons for the high stroke incidence among persian are not yet clear. it is the first gene-association study in persian population, which determines the relationship between 25 gene v...