نتایج جستجو برای: translatability
تعداد نتایج: 489 فیلتر نتایج به سال:
The immunoglobulin mu heavy chain gene of mouse hybridoma cells is expressed in two forms, microseconds and microns, differing in their use of 3' exons. As for many other mammalian genes, mutations in the mu gene which prematurely terminate translation often have the effect of reducing the amount of these mu RNAs. To test the generality of this relationship, we selected mutant hybridoma cell li...
A workshop took place in 2015 to follow up TREAT-NMD activities dedicated to improving quality in the preclinical phase of drug development for neuromuscular diseases. In particular, this workshop adressed necessary future steps regarding common standard experimental protocols and the issue of improving the translatability of preclinical efficacy studies.
The deficiency of robust and practical methods for 18F-radiofluorination is a bottleneck for positron emission tomography (PET) tracer development. Here, we report the first transition-metal-assisted 18F-deoxyfluorination of phenols. The transformation benefits from readily available phenols as starting materials, tolerance of moisture and ambient atmosphere, large substrate scope, and translat...
This work is a sequel to our 14]. It is shown how Theorem 6 of 14], dealing with the translatability of HA (Heyting's arithmetic) into negationless arithmetic NA, can be extended to the case of intuition-istic arithmetic in higher types.
XML data management using relational database systems has been intensively studied in the last few years. However, in order for such systems to be viable, they must support not only queries, but also updates over virtual XML views that wrap the relational data. While view updating is a long-standing difficult issue in the relational context, the flexible XML data model and nested XML query lang...
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