PURPOSE Patients with testicular seminoma may face fertility issues because of their underlying disease as well as treatments they undergo. The current patterns of practice among U.S. radiation oncologists aimed at assessing and preserving fertility in patients with Stage I seminoma are unknown. METHODS We surveyed practicing U.S. radiation oncologists via an Institutional Review Board-approv...

To carry out an in-depth analysis of the scientific research on male infertility, we performed the first bibliometric analysis focusing on studies involving male infertility worldwide during the period 1995-2014. Analysis of 6357 articles in the field of male infertility showed a significant increasing trend in the number of publications over the period 1995-2014. Obstetrics and Gynecology was ...

Aim. Ovarian epithelial dysplasia was initially described in material from prophylactic oophorectomies performed in patients at genetic risk of ovarian cancer. Similar histopathological abnormalities have been revealed after ovulation stimulation. Since infertility is also a risk factor for ovarian neoplasia, the aim of this study was to study the relationship between infertility and ovarian dy...

Background: Little is known about how to predict post-treatment reproductive health outcomes in reproductive-age women with cancer. We sought to determine whether predictors like age, parity, temporary post-treatment amenorrhea, or posttreatment infertility are associated with reproductive compromise. Methods: We contacted 2532 women from a statewide cancer registry (randomly sampled; diagnosed...

Recent reports have drawn attention to the increasing prevalence of sexually transmitted infections (STIs) in the UK. This trend has been most apparent in young people aged 16-19. STIs are associated with several potentially serious health outcomes, including infertility and cervical cancer. This briefing describes recent trends in the sexual health of 16-19 year olds, discusses potential contr...

Background: Declines in semen quality over time are not well understood. It is suspected that infectious disease may affect reproductive function. The aim of this study was to investigate semen quality in men in infertile relationships who were under investigation for couple infertility and attended a clinic for routine semen analysis over a period of 15years. Materials and Methods: We investig...

Apparent rise in the incidence of infertility in females and the trend shifting towards delayed child bearing brought up the concept of ovarian ageing. Women in their early thirties show poor ovarian reserve which is an entity named as early ovarian ageing. Early ovarian ageing is mostly genetically determined, but acquired modifiable factors like smoking, or ovarian surgery have some roles. In...

Infertility affects one in six couples in the United Kingdom. Male infertility is now the single most common cause. Compared with animals, human conception is, at best, inefficient. From one act of coitus a man can eject some 500 million sperm, yet a mere hundred survivors will reach the ovum. As a result anything less than 20 million sperm per ml of ejaculate significantly reduces the chance o...

BACKGROUND In recent years, oxidative stress has been studied extensively as a main contributing factor to male infertility. Nitric Oxide, a highly reactive free radical gas, is potentially detrimental to sperm function and sperm DNA integrity at high levels. Thus, the aim of this study was to investigate the associations between five polymorphisms in nitric oxide synthase genes (NOSs) and the ...

BACKGROUND There is a growing body of evidence that testicular function has decreased rapidly over the last 50 years. However, much less is known about corresponding trends in ovarian function. Herein, we examine the temporal changes in ovarian function in a large sample of infertile patients from the Czech Republic over a period of 14 years. METHODS In a retrospective study, we analysed a la...