Microporous ceramic material, based on β-tricalcium phosphate β-Ca3(PO4)2 with grain size 2–5 μm, pore smaller than 10 mm, and density 1.22 g/cm3 corresponding to ~40% of the theoretical (3.07 g/cm3) β-Ca3(PO4)2, was obtained from a powder mixture given molar ratio Ca/P = 1.5 after firing at 1100 °C. A homogenized synthetic dicalcium hydrogen phosphates 1 calcium citrate tetrahydrate Ca3(C6H5O7...

both anorganic bovine bone (abb) and β-tricalcium phosphate (β-tcp) are used in clinical practice as bone substitute materials, but there is limited data comparing these two materials in standardized defects. the aim of this study was to histologically evaluate the effectiveness of abb and β-tcp in the healing of experimentally induced bone defects.eighteen bone defects were created on the calv...

Foraminifera carbonate exoskeleton was hydrothermally converted to biocompatible and biodegradable zinc-tricalcium phosphate (Zn-TCP) as an alternative biomimetic material for bone fracture repair. Zn-TCP samples implanted in a rat tibial defect model for eight weeks were compared with unfilled defect and beta-tricalcium phosphate showing accelerated bone regeneration compared with the control ...

PURPOSE To investigate the effect of platelet rich fibrin (PRF) and beta tricalcium phosphate (β-TCP), alone or in combination, on bone regeneration in pig tibial defects. METHODS Four standardized defects were prepared in both tibias of three adult male pigs. The first defect was left unfilled as a control; the others were grafted with either PRF, β-TCP or PRF mixed with β-TCP. All animals w...

Tricalcium-silicate and Tetracalcium-phosphate were prepared from ultra-pure chemical compounds via solid-state reaction at 1450 o C and 1500 o C respectively in an attempt to formulate a root end filling cement. Materials were investigated by X-ray diffraction and Transmission-electron microscope. The formulated cement comprises 60 wt% Tricalcium-silicate, 20 wt% Tetracalcium-phosphate and 20 ...

The need for bone graft materials to fill bony voids or gaps that are not related to the intrinsic stability of the bone that arise due to trauma, tumors or osteolysis remains a clinically relevant and significant issue. The in vivo response of collagen-tricalcium phosphate bone graft substitutes was evaluated in a critical size cancellous defect model in skeletally mature rabbits. While the ma...