IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND (SYSTEMATIC NAME: triethyl-ammonium 2,5-dichloro-4-hy-droxy-3,6-dioxo-cyclo-hexa-1,4-dien-1-olate), C(6)H(16)N(+)·C(6)HCl(2)O(4) (-), two hydrogen chloranilate anions are connected by a pair of bifurcated O-H⋯O hydrogen bonds into a dimeric unit. The triethyl-ammonium cations are linked on both sides of the dimer via bifurcated N-H⋯O hydrogen bonds...

The asymmetric unit of the title compound, C(6)H(16)N(+)·C(3)H(2)N(3)S(3) (-), contains two independent ion pairs. The 2,4,6-trithioxo-1,3,5-triazinan-1-ide anion features an almost planar six-membered ring (r.m.s. deviations = 0.009 and 0.018 Å) having exocyclic double-bond S atoms. The anions inter-act by N-H⋯S hydrogen bonds to generate a chain running along [110]. The triethyl-ammonium cati...

The title 20-crown-6 unit, C(28)H(30)Br(2)O(6)·CH(2)Cl(2), consisting of three benzo groups and triethyl-ene glycol was prepared from the reaction of 1,2,4,5-tetra-kis-(bromo-meth-yl)benzene and bis-phenol in the presence of sodium hydride. In the crystal, one O atom of the central ethyl-ene glycol in the triethyl-ene glycol unit exhibits an exo conformation as a result of intra-molecular C-H⋯O...

Lansoprazole fast-disintegrating tablet (LFDT) is a new patient-friendly formulation of lansoprazole. Since lansoprazole is an antiulcer agent and is unstable under acidic conditions, we have developed LFDT as an orally disintegrating tablet containing enteric-coated microgranules. The effect of compression on dissolution behavior was investigated, as compression affected cleavage and crushing ...

An economical and environmental friendly method has been developed for the synthesis of Schiff base ligand N,N'bis(2-hydroxy-1-naphthylidene)-4-hydroxyphenylmethanediamine by one pot three components reaction of 2hydroxy-1-naphthaldehyde , 4-hydroxy benzaldehyde and ammonium acetate salt in the presence of triethyl amine under solvent free condition at room temperature. Cu(II), Ni(II) and Zn(II...

A simple, selective, and sensitive liquid chromatographic method has been developed and validated for quantitative determination of Imatinib mesylate in rat serum. Efficient chromatographic separation has been performed on a Zorbax Extend (5 microm, 4.6 x 250 mm) double end-capped C(18) column using a mobile phase consisting of methanol and aqueous triethyl amine (pH 10.5; 1%, v/v) (60:40, v/v)...

A novel stability-indicating gradient RP-UPLC method was developed for the quantitative determination of process related impurities and forced degradation products of fexofenadine HCl in pharmaceutical formulations. The method was developed by using Waters Aquity BEH C18 (100 mm x 2.1 mm) 1.7 μm column with mobile phase containing a gradient mixture of solvent A (0.05% triethyl amine, pH adjust...

A simple and rapid reverse-phase high-performance liquid chromatography method is developed for the simultaneous determination of selective serotonin reuptake inhibitors (sertraline, citalopram, paroxetine and fluoxetine) in urine, plasma and oral fluid. Separation was performed on a Crestpack-18 column (4.6 × 250 mm × 5 µ) within 17.5 min. The mobile phase was composed of water (50 mL) [with g...