نتایج جستجو برای: tumor microenvironment

تعداد نتایج: 441627  

Journal: :Oncology reports 2015
Zi Wang Zhixi Li Yuyi Wang Dan Cao Xia Wang Ming Jiang Mei Li Xi Yan Yan Li Yanyang Liu Feng Luo

The systematic application of antiangiogenic therapy remains an issue of concern, mainly due to the hypoxic and inflammatory changes in the tumor microenvironment elicited by antiangiogenic therapy. Versican, a 'bridge' connecting inflammation with tumor progression as well as playing a central role in the generation of an inflammatory tumor microenvironment is a promising candidate for the int...

Journal: :Frontiers in bioscience : a journal and virtual library 2005
Jianbiao Zhou Katja Mauerer Lucia Farina John G Gribben

The tumor microenvironment is essential for tumor cell proliferation, angiogenesis, invasion, and metastasis by providing survival signals and a sanctuary site for tumor cells, by secretion of growth factors, pro-angiogenesis factors and direct adhesion molecule interactions. Our knowledge of microenvironment is only now beginning to unfold. In this review, the morphological and molecular chara...

2016
Bo Zhang Wei Shi Ting Jiang Lanting Wang Heng Mei Heng Lu Yu Hu Zhiqing Pang

Effective delivery of nanomedicines to tumor tissues depends on both the tumor microenvironment and nanomedicine properties. Accordingly, tumor microenvironment modification or advanced design of nanomedicine was emerging to improve nanomedicine delivery to tumors. However, few studies have emphasized the necessity to optimize the tumor microenvironment and nanomedicine properties simultaneousl...

Journal: :BIO web of conferences 2022

Tumor immune escape is one of the ten characteristics tumor occurrence and development. Immunotherapy targeting has achieved remarkable success in recent years. involves many factors links, which are related to changes cells themselves microenvironment, mechanism complex. At present, it still faces great challenges clinical practice. This article introduces from several aspects, including itsel...

Journal: :Carcinogenesis 2015
Stephanie C Casey Monica Vaccari Fahd Al-Mulla Rabeah Al-Temaimi Amedeo Amedei Mary Helen Barcellos-Hoff Dustin G Brown Marion Chapellier Joseph Christopher Colleen S Curran Stefano Forte Roslida A Hamid Petr Heneberg Daniel C Koch P K Krishnakumar Ezio Laconi Veronique Maguer-Satta Fabio Marongiu Lorenzo Memeo Chiara Mondello Jayadev Raju Jesse Roman Rabindra Roy Elizabeth P Ryan Sandra Ryeom Hosni K Salem A Ivana Scovassi Neetu Singh Laura Soucek Louis Vermeulen Jonathan R Whitfield Jordan Woodrick Annamaria Colacci William H Bisson Dean W Felsher

Potentially carcinogenic compounds may cause cancer through direct DNA damage or through indirect cellular or physiological effects. To study possible carcinogens, the fields of endocrinology, genetics, epigenetics, medicine, environmental health, toxicology, pharmacology and oncology must be considered. Disruptive chemicals may also contribute to multiple stages of tumor development through ef...

Journal: :BioMed Research International 2019

Journal: :Chinese Medical Journal 2021

Journal: :Molecular Biology: Open Access 2012

Journal: :Journal of Magnetic Resonance Imaging 2002

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