introduction: c - reactive protein (crp) is an acute-phase plasma protein that can be used as a marker of activation of the immune system. in response to several inflammatory reactions,the concentration of crp increases and recently have been applicated as a cancer detector in some studies. we aimed to evaluate the relation between crp level and the staging and grading of gastric and colon mali...

esophageal cancer is a lethal disease with poor survival rate. it is necessary to determine the extension, and the stage of the tumor to predict the outcome of patients. of the two common pathologic types, squamous cell carcinoma is still the most common form, and adenocarcinoma is the leading one. early diagnosis and radical treatment of esophageal cancer, regardless of tumor spreading, increa...

Background: Breast cancer is formed of a neoplastic component (epithelial) and a non-neoplastic component (stroma). Stromal- stromal and tumor- stromal interactions have been shown in the regulation of cancer cell growth, metastatic capacity and outcome of treatment. Tumor-associated macrophages (TAMs) are a component of tumor stroma reactionsand are considered as an important ...

discoidin domain receptor (ddr) is a new member of the receptor tyrosine kinase family. there are two isoforms of discoidin domain receptor (ddr), ddr1 and ddr2. these receptors play a major role in the adhesion, motility and cell proliferation. due to the important role of ddr2 in the development of tumor extension, this receptor is pivotal in the field of carcinogenesis. the aim of this study...

Esophageal cancer is a lethal disease with poor survival rate. It is necessary to determine the extension, and the stage of the tumor to predict the outcome of patients. Of the two common pathologic types, squamous cell carcinoma is still the most common form, and adenocarcinoma is the leading one. Early diagnosis and radical treatment of esophageal cancer, regardless of tumor spreading, increa...

This study aims to refine the designation for single hepatocellular carcinoma (HCC) >5 cm by comparing the postresection prognosis of these patients with those who have a single-tumor ≤5 cm and those with stage B.Patients with a single-tumor were classified into subgroups based on diameter. Of the 1132 patients analyzed, 426 had a single-tumor >2 and ≤5 cm; 229, a single-tumor >5 and ≤8 cm; 52,...

PURPOSE To investigate the correlated factors for lymph node metastasis and prognosis for patients with T2 gastric cancer. METHODS A total of 442 patients with T2 gastric cancer who underwent gastrectomy from January 1996 to December 2009 were evaluated. The clinicopathological parameters were analyzed for lymph node metastasis and prognosis, including gender, age, tumor size, tumor location,...

background: mucinous adenocarcinoma colorectal cancer present at a more colorectal advanced stage of disease and showe a poorer prognosis than those with other types of carcinoma. the purpose of the present study was to clarify the clinicopathological characteristics of mucinous colorectal carcinoma in the iranian population. methods: 110 patients with mucinous adenocarcinoma were selected from...